Chapter 8 Microbial genetics
Chapter 8 Microbial genetics
Chapter outline 8.1 Mutations and Mutants 8.2 Genetic Recombination 8.3 Genetic Transformation 8.4 Transduction 8.5 Conjugation 8.6 Plasmids 8.7 Transposons and Insertion Sequences 8.8 Comparative Prokaryotic Genomics
8.1 Mutations and Mutants 8.2 Genetic Recombination 8.3 Genetic Transformation 8.4 Transduction 8.5 Conjugation 8.6 Plasmids 8.7 Transposons and Insertion Sequences 8.8 Comparative Prokaryotic Genomics Chapter outline
Concepts 。 DNA replication is a very complex process involving a variety of proteins and a number of steps.It is designed to operate rapidly while minimizing errors and correcting those that arise when the DNA sequence is copied. The actual transfer of genetic material between bacteria usually takes place in one of three ways:direct transfer between two bacteria temporarily in physical contact (conjugation),transfer of a naked DNA fragment (transformation),or transport of bacterial DNA by bacteriophages (transduction)
Concepts • DNA replication is a very complex process involving a variety of proteins and a number of steps. It is designed to operate rapidly while minimizing errors and correcting those that arise when the DNA sequence is copied. • The actual transfer of genetic material between bacteria usually takes place in one of three ways: direct transfer between two bacteria temporarily in physical contact (conjugation), transfer of a naked DNA fragment (transformation), or transport of bacterial DNA by bacteriophages (transduction)
Importance of study on microbial genetics simple systems 。 studying genetic phenomena useful tools decipher the genetics mechanisms *molecular cloning isolate and duplicate specific genes from other organisms genes are manipulated and placed in a microorganism where they can be induced to increase in numbers
❖ simple systems • studying genetic phenomena ❖ useful tools • decipher the genetics mechanisms ❖ molecular cloning • isolate and duplicate specific genes from other organisms • genes are manipulated and placed in a microorganism where they can be induced to increase in numbers Importance of study on microbial genetics
Value in industry Antibiotics Increase yields and improve manufacturing processes Diseases Understanding the genetics of disease-causing microorganisms Genetic transfer in prokaryotes How genes can be transferred from one organism to another,even from one species to another
❖ Value in industry • Antibiotics • Increase yields and improve manufacturing processes ❖ Diseases • Understanding the genetics of disease-causing microorganisms ❖ Genetic transfer in prokaryotes • How genes can be transferred from one organism to another, even from one species to another