Table 19.2 Proofreading reduces the errors made by DNA polymerases. Enzyme Synthetic Proofreading 〓 ror rate domain domain proof +proof 三coi DNApol I aa 200-600 Teminal 10 5×107 三coi DNA pol a subunit e subunit 7×1065×109 T4 DNA C-teminal pol Teminal 5×105107 T DNA pol ? 118145 10 10 Reverse transcript None 10 ase
Eble 193 There ane 5 anmian INApolynmerases (dentifed by reekletters; yeastequvalents are given Rbnannnmeraks). INA 6红III)E(II) BY Polyerase Location Nubar Nubar Nubar Nicobar M chondri al Fuction Lagging Leading Repair RepIcation stand synthesis synthesi prim g Reative 80%o 1015902-1590 actty Mass(dalt 300,000 170 25000040,000 180 ns 230000 300000 Stbun'ts Catalytic Catalytic Catalytic Catalytic Catalytic 2 primase I unkown l ukon 2 unkown l ukon requres PNA exoncbas D deoxythy N efect Nb efect wEak hibitory Ihbitbry mine Aphidicolin IhbibryIhbibry Ihbibry Nb efect N efec
Fle3位4 set tb A one
r,1 HHHHHHH