Clinical Features of Cushing's syndrome Bone Osteoporosis Vertebral collapse Pathologic fractures Osteonecrosis of the femoral and humeral heads Muscle Proximal myopathy (lower limb and shoulder girdle
Clinical Features of Cushing’s Syndrome • Bone • Osteoporosis • Vertebral collapse • Pathologic fractures • Osteonecrosis of the femoral and humeral heads • Muscle • Proximal myopathy (lower limb and shoulder girdle )
Clinical Features of Cushing's syndrome Cardiovascular ypertension Cardiovascular events and thromboembolic events
Clinical Features of Cushing’s Syndrome • Cardiovascular • Hypertension • Cardiovascular events and thromboembolic events
Clinical Features of Cushing's syndrome Infections Tuberculosis Fungal infections of the skin and nails Wound infections and poor wound healing
Clinical Features of Cushing’s Syndrome • Infections • Tuberculosis • Fungal infections of the skin and nails • Wound infections and poor wound healing
Clinical Features of Cushing's syndrome Metabolic and endocrine Glucose intolerance and overt diabetes Elevated cholesterol and triglycerides Hypokalemic alkalosis
Clinical Features of Cushing’s Syndrome • Metabolic and Endocrine • Glucose intolerance and overt diabetes • Elevated cholesterol and triglycerides • Hypokalemic alkalosis
Clinical Features of Cushing's syndrome Eve Raised intraocular pressure and exophthalmos Cataracts Chemosis
Clinical Features of Cushing’s Syndrome • Eye • Raised intraocular pressure and exophthalmos • Cataracts • Chemosis