Some Aldehydes and Ketones 十十 Androstenedione testosterone 雄甾酮 雄（甾）烯二酮 KAIZEN ANDROSTENEDION
Some Aldehydes and Ketones Some Aldehydes and Ketones O O H H H And rosten edion e O OH H H H testoste ron e 雄 ( 甾 )烯二酮 雄甾酮
Section J1 Preparation Functional group transformations >Aldehydes can be synthesized by the oxidation of primary alcohols, or by the reduction of esters,acid chlorides,or nitriles. >Ketones can be synthesized by the oxidation of secondary alcohols. >Carbon-carbon bond formation >C-C Bond cleavage
Section Section J1 Preparation J1 Preparation ¾Functional group transformations ¾Aldehydes can be synthesized by the oxidation of primary alcohols, or by the reduction of esters, acid chlorides, or nitriles. ¾Ketones can be synthesized by the oxidation of secondary alcohols. ¾Carbon-carbon bond formation ¾C-C Bond cleavage
Functional group transformations Aldehydes can be synthesized by the oxidation of primary alcohols ,or by the reduction of esters,acid chlorides,or nitriles. KCN 1.DIBAH,toluene 0 R一X R一C三N 2.H30© Alkyl halide R Nitrile 二异丁基氢化铝 Fig.1.Synthesis of an aldehyde from an alkyl halide with 1C chain extension
1. Functional group transformations Aldehydes can be synthesized by the oxidation of primary alcohols ,or by the reduction of esters, acid chlorides, or nitriles. 二异丁基氢化铝
Oxidation of Alcohols OH Compounds with two hydrogen atoms attached to the alcohol give aldehydes and then acids. Cr202
Oxidation of Alcohols H OH OH H O H Cr 2 O 7 -2 HO O Compounds with two hydrogen atoms attached to the alcohol give aldehydes and then acids. Cr 2 O 7 -2 OH H O
Oxidation of Alcohols general reaction: Compounds with one hydrogen atom attached to the alcohol give ketones. Compounds with no hydrogen atoms attached to the alcohol carbon do not react. Cr2072 no reaction
Oxidation of Alcohols general reaction: O O H H [O ] Compounds with one hydrogen atom attached to the alcohol give ketones. Cr 2 O 7 -2 O H Compounds with no hydrogen atoms attached to the alcohol carbon do not react. no reaction