Interaction of cells and extracellular matrix a network of collagen fibrils( c)in the underlying connective tissue interacts with the lower face of the lamina Some of the epithelial cells(e) have been removed to expose the upper surface of the mat like basal lamina ( bl)
Interaction of cells and extracellular matrix Some of the epithelial cells (E) have been removed to expose the upper surface of the mat like basal lamina (BL). A network of collagen fibrils (C) in the underlying connective tissue interacts with the lower face of the lamina
Interaction of cells and extracellular matrix mn The shaping of the extracellular matrix by cells
The shaping of the extracellular matrix by cells Interaction of cells and extracellular matrix
Interaction of cells and extracellular matrix founder cell in epithelium The simplest BD mechanism by intercel lular which cells junction assemble to form a tissue basal lamina enlarged epithelium The progeny of the founder cell are retained in the epithelium by the basal lamina and by cell-cell adhesion mechanisms, including the formation of intercellular junctions
The progeny of the founder cell are retained in the epithelium by the basal lamina and by cell-cell adhesion mechanisms, including the formation of intercellular junctions. Interaction of cells and extracellular matrix The simplest mechanism by which cells assemble to form a tissue
Basal laminae perform diverse functions MUSCLE EPITHELIAL SHEET KIDNEY GLOMERULUS LUMEN basal lamina connective tissue endothelial cell BLOOD MAMMa. muscle plasma membrane The basal lamina serves as the permeability barrier determining which molecules will pass into the urine from the blood
The basal lamina serves as the permeability barrier determining which molecules will pass into the urine from the blood Basal Laminae Perform Diverse Functions
Interaction of cells and extracellular matrix a defined ELL DIES amount of BY APOPTOSIS fibronectin in single patch the same amount of CELL SPREADS fibronectin SURVIVES distributed in AND GROWS small spot 50 um For many cells, contact with the extracellular matrix is essential for survival, growth, and proliferation
Interaction of cells and extracellular matrix For many cells, contact with the extracellular matrix is essential for survival, growth, and proliferation