thymus gland 1. Cells: thymic stromal cells(Tsc) thymocytes cell(ap+) monocytes, macrophage, DC 2. Structure: cortex---immature thymocytes madulla---mature thymocytes Mo, DC 3. Function: It is the site of T cell maturation It determines the specificity of the TCR expressed on the t cells released to periphery
thymus gland 1.Cells: thymic stromal cells(TSC) thymocytes T cell (αβ+ ) monocytes, macrophage, DC 2.Structure:cortex---immature thymocytes madulla---mature thymocytes Mø,DC 3.Function: It is the site of T cell maturation; It determines the specificity of the TCR expressed on the T cells released to periphery
thy mus lung (heart capsule cortical trabeculae epithelial cell Cortex ub capsular thymocyte epithelium (b one marrow or rico- medullar junction medullary epithelial cell dendritic cell Medulla (bone marrow Hassalls origin) corpus macrophage (bone marrow origin) The cellular organization of the human thymus
The cellular organization of the human thymus
spleen 1. adult spleen: 13*8cm 180-250g 2, the white pulp: lymphoid cells the red pulp venous sinuses cellular coras 3. function: a reservoir for platelets erythrocytes and granulocytes destroy the ag aged platelets
spleen 1. adult spleen:13*8cm 180-250g 2. the white pulp: lymphoid cells the red pulp venous sinuses cellular cords 3.function:a reservoir for platelets, erythrocytes and granulocytes; destroy the Ag, aged platelets
spleen Gastric surface Renal surface Splenic artery Splenic vein (b) Capsule Trabecula Primary Vascular follicle sinusoid Margina zone ,White pulp Periarteri lymphatic heath (Pals) Red pulp Germinal center Vein Art ry
spleen
A Central artery .T cell zone (periarteriolar lymphoid 2 sheath [PALSD Red . pulp Margina B cell zone zone -Trabecular Germinal (secondary artery center B Germinal center of lymphoid Periarteriolar follicle monoid. sheath(PALS) ElsevierAbbas&Lichtman:BasicImmunologyUpdated2e-www.studentconsult.co Downloaded from Student Consult (on 1 June 2006 02: 08 PM)
Downloaded from: StudentConsult (on 1 June 2006 02:08 PM) © 2005 Elsevier