Physiological and pathological representation of immune response Function Physiological Pathological (advantageous)(harmful) immune defense resist to pathogen hypersensitivity/ immunologic d eficiency disease mmune scavenge damaged Autoimmune homeostasis or senile cell disease Immune Scavenge cells with cancer surveillance misreplication/ virus persistent mutant cell infection
Function Physiological (advantageous) Pathological (harmful) immune defense resist to pathogen hypersensitivity/ immunologic deficiency disease immune homeostasis scavenge damaged or senile cell Autoimmunne disease immune surveillance Scavenge cells with misreplication/ mutant cell Cancer virus persistent infection Physiological and pathological representation of immune response
Immune system a dominate immune function execute immune effect B comprise immune organs, immune cells and immune molecules
Immune system dominate immune function execute immune effect comprise immune organs, immune cells and immune molecules
adenoid right subclavian vein left subclavian vein thymus lymph node heart thoracic duct kidney 身 spleen Peyer's patch in small intestine appendix large intestine lymphatics bone marrow
I Immune organs center immune organs Concept places where immunocytes genesis, develop, differentiate and mature Composition: bone marrow, thymus and bursa of Fabricius(which is one of Avian character) peripheral immune organs Concept: places where mature T, b lymphocytes resident and contact with antigens and carry out Immune response composition: lymph node, spleen, mucosal-associated lymphoid tissue
1 Immune organs center immune organs concept：places where immunocytes genesis, develop, differentiate and mature composition ： bone marrow, thymus and bursa of Fabricius (which is one of Avian character) peripheral immune organs concept ： places where mature T, B lymphocytes resident and contact with antigens and carry out immune response composition：lymph node, spleen, mucosal-associated lymphoid tissue
Bone marrow 1. the place in which proliferation of HSC take place 2. the place in which development and maturation of b cells occur 3. Secondary humoral response and produce antibodies
1. the place in which proliferation of HSC take place 2. the place in which development and maturation of B cells occur 3. Secondary humoral response and produce antibodies Bone marrow