如x学营命 肥胖与糖尿病和基因 张成宁 zhangxianning@zju.edu.cn Tel:13105819271:88208367 Office: C303, Teaching building 2017/04
肥胖与糖尿病和基因 张咸宁 zhangxianning@zju.edu.cn Tel：13105819271; 88208367 Office: C303, Teaching Building 2017/04
Narayan Km, et al. Lifetime risk for Diabetes mellitus in the united states JAM42003;290(14):1884-1890 It has been estimated that one in every three individuals (one in two minorities) born in the us in the year 2000 will develop diabetes in their lifetime, mainly due to the epidemic of obesity
Narayan KM, et al. Lifetime Risk for Diabetes Mellitus in the United States. JAMA 2003; 290 (14): 1884–1890 • It has been estimated that one in every three individuals (one in two minorities) born in the US in the year 2000 will develop diabetes in their lifetime, mainly due to the epidemic of obesity
Demmer rt, et al. Prevalence of diagnosed and undiagnosed type 2 diabetes mellitus among Us adolescents, results from the continuous nHANES, 1999-2010 AmJ Epidemiol 2013 178(7):1106-1113 Estimates of the prevalences of type 1 and type 2 diabetes were 0.48% and 0.369, respectively, indicating that T2DM accounted for 43% of all cases Further, undiagnosed T2DM prevalence was.12%, representing 34% of T2DM cases. T2DM accounts for approximately half of adolescent dia betes in the us. and one-third of these cases are undiagnosed
Demmer RT, et al. Prevalence of diagnosed and undiagnosed type 2 diabetes mellitus among US adolescents: results from the continuous NHANES, 1999-2010. Am J Epidemiol 2013; 178(7): 1106-1113 • Estimates of the prevalences of type 1 and type 2 diabetes were 0.48% and 0.36%, respectively, indicating that T2DM accounted for 43% of all cases. Further, undiagnosed T2DM prevalence was 0.12%, representing 34% of T2DM cases. T2DM accounts for approximately half of adolescent diabetes in the US, and one-third of these cases are undiagnosed
Energy intake Energy storage 合 Energy expenditure
肥胖( obesity):体内脂肪积聚过多导致的一种 由多种因素引起的慢性代谢性疾病。患者常因过 多摄食或机体代谢发生改变而导致体内脂肪积聚 过多,体重增加,并引起病理生理方面的改变。 体重指数≥28.0kg/m2 The increasing prevalence of obesity worldwide (an approximate doubling in the last 30 years) 单纯性肥胖患者全身脂肪分布比较均匀,没有 内分泌紊乱现象,也无代谢障碍性疾病,其家 族往往有肥胖病史
肥胖（obesity）:体内脂肪积聚过多导致的一种 由多种因素引起的慢性代谢性疾病。患者常因过 多摄食或机体代谢发生改变而导致体内脂肪积聚 过多，体重增加，并引起病理生理方面的改变。 体重指数 ≥ 28.0 kg/m² • The increasing prevalence of obesity worldwide (an approximate doubling in the last 30 years) • 单纯性肥胖患者全身脂肪分布比较均匀，没有 内分泌紊乱现象，也无代谢障碍性疾病，其家 族往往有肥胖病史