公公 There are 3 main bacterial meningeal pathogens 1. Haemophilus influenzae 2. Neisseria meningitides 3. Streptococcus pneumoniae *Incidence varies by region and age
*There are 3 main bacterial meningeal pathogens: 1. Haemophilus influenzae 2. Neisseria meningitides 3. Streptococcus pneumoniae *Incidence varies by region and age
公公 Haemophilus influenzae a Small GN, pleomorphic coccobac 2 H flu type B causes almost ALL invasive disease a Nontypeable Hib can rarely cause meningitis. 7 Incidence of hib decreased by 97% after vaccine
Haemophilus influenzae Small GN, pleomorphic, coccobacilli H. flu type B causes almost ALL invasive disease Nontypeable Hib can rarely cause meningitis. Incidence of Hib decreased by 97% after vaccine
公公 +Occurs predominantly in infants 2mo to 2yr of age Many cases are in winter Higher incidence of subdural effusion
Occurs predominantly in infants 2mo to 2yr of age Many cases are in winter Higher incidence of subdural effusion
Neisseria meningitidis 公公 Gn diplococci Serotypes A, B, C,Y, and W135 cause most invasive di sease. Virulence depends on: C capsular polysaccharide 2. LPS(endotoxin) 3. Pili 4.IgA protease 5. ompS gene
Neisseria meningitidis - GN diplococci - Serotypes A,B,C,Y, and W135 cause most invasive disease. - Virulence depends on: 1. Capsular polysaccharide 2. LPS(endotoxin) 3. Pili 4. IgA protease 5. ompS gene
公公 Occur in epidemics(type A, C), which Is more common In spring, or sporadic all the year(type B,C,Y
Occur in epidemics (type A,C), which is more common in spring, or sporadic all the year (type B,C,Y)