Figure 1. 19 (a)The microscope used by Robert Hooke (be)Two drawings by Robert Hook of rst microscopic descriptions of microorganisms. (b)A blue mold growing on the surface of leather; the round structures contain spores of the muld. c)A mold growing on the surface of an aging, deteriorating ruse leaf
Antony van Leeuwenhoek (1632-1723) and his microscope Louis Pasteur(1822-1895) working in his laboratory
• Antony van Leeuwenhoek (1632-1723) and his microscope. • Louis Pasteur (1822-1895) working in his laboratory
Air forced out ) (a) Nonsterile liquld of flask Liquid sterilized poured into flask drawn out in Dust and microorganisms Liquid cooled Liquid remains slowly sterile for nany years Short time Microorgani grow in liquid liquid
Robert Koch (1843 1910 EXamining specImen in his laboratory
• Robert Koch (1843- 1910) Examining a specimen in his laboratory
Chapter 1 Introduction: An Overview of Microbiology and Cell Biology Postulate 1 organism should be preser in all cases of the diseas blood and absent from healthy animEs Suspecter Red blood cell Postulate 2 Streak agar plate with sample from ethe should be grow dIseased or healthy animal Colonie Inoculate healthy imal with cells suspected pathogen Postulate 3 Cells from n pute culture should cause disease in a Diseased ove blood or e sample and arve by microscopy Postulate 4 The organism should be Laboratory ed and show culture Figure 1.22 Koch's postulates for prov o original lowing isolation of a pure culture of the st Suspected pathogen Pure culture pected pathogen, a laboratory culture of th organism organism should both initiate the disease ar