·pre-sinusoidal obstructionsThe main cause is schistosomial cirrhosisSchistosomial eggs depositin small branches withperipheral granulation,resulting in obstruction中央静脉of blood flow and increase肝窦门静脉of portal vein pressure肝动脉小芬支小分支交通支
• pre-sinusoidal obstruction: The main cause is schistosomial cirrhosis Schistosomial eggs deposit in small branches with peripheral granulation, resulting in obstruction of blood flow and increase of portal vein pressure
.post-sinusoidal obstructionsThemain causeispost-hepatitis cirrhosisFibroplasiaandregenerationofhepaticcellscompressthehepatic sinus,reducing in obstructed bloodflowandincreasedportalveinpressure中央静脉肝窦门静脉肝动脉小分支小分支交通支
• post-sinusoidal obstruction: The main cause is post-hepatitis cirrhosis (1)Fibroplasia and regeneration of hepatic cells compress the hepatic sinus, reducing in obstructed blood flow and increased portal vein pressure
(2)Theshuntsbetweenterminalhepaticarteriesandportal veinsopen,andthehepaticarteriesbloodflow withhigh-pressure perfusedirectlyintolow-pressured portal veins,whichcontributestoportal hypertension中央静脉肝窦hepatic门静脉arteries肝动脉小芬支小分支交通支portal veins
(2)The shunts between terminal hepatic arteries and portal veins open, and the hepatic arteries blood flow with high-pressure perfuse directly into low-pressured portal veins, which contributes to portal hypertension portal veins hepatic arteries
(3)Thehighhepaticresistance can affectthehepaticlymphaticback-flow,whichwill further increasethe portal pressure
(3)The high hepatic resistance can affect the hepatic lymphatic back-flow, which will further increase the portal pressure
CIRRHOSISCENT