Site of disease TB can involve any region of Gl tract; eum and cecum Ascending colon Jejunum Duodenum Stomach Esophagus Sigmoid colon rectum Fudan University ZhongshanHlespitam
Fudan University Zhongshan Hospital www.themegallery.com Site of disease TB can involve any region of GI tract; • Ileum and cecum • Ascending colon • Jejunum • Duodenum • Stomach • Esophagus • Sigmoid colon • rectum
Why is ileocecal region Its richness of lymphoid tissue · Relative stasis Increased absorption rate Fudan University ZhongshanHlespitam
Fudan University Zhongshan Hospital www.themegallery.com Why is ileocecal region? • Its richness of lymphoid tissue • Increased absorption rate • Relative stasis
Pathogenesis of TB: Infection Immunity Fudan University ZhongshanHlespitam
Fudan University Zhongshan Hospital www.themegallery.com Infection - Immunity Pathogenesis of TB:
FORMS OF GITB Ulceroconstrictive Hypertrophic 60% of patients 10% of patients Highly virulent Chronic Mostly small Intestinal Mostly ileocaecal Mixed 30% of patients (Howell& knapton, 196 Fudan University Zhongshan Hgspitalm
Fudan University Zhongshan Hospital www.themegallery.com FORMS OF GI TB Ulceroconstrictive 60% of patients Highly virulent Mostly small Intestinal Hypertrophic 10% of patients Chronic Mostly Ileocoecal Mixed 30% of patients (Howell & Knapton, 1964)
Three ty pes of intestinal tuberculosis Ulcerative lesion(common) Hypertrophic lesion Ulcerohy peritrophic lesions Fudan University ZhongshanHlespitam
Fudan University Zhongshan Hospital www.themegallery.com Three types of intestinal tuberculosis • Ulcerative lesion(common) • Hypertrophic lesion • Ulcerohypertrophic lesions