Part1 Blast软件的使用 一段序列 Blast 同源序列 多序列比对 系统发育树
Part 1 Blast软件的使用 11 一段序列 同源序列 多序列比对 系统发育树 Blast MEGA Blast
◆ BLAST( Basic local alignment Search Too)即碱基局部对准检索 工具,是一种序列类似性检索工具。它采用统计学记分系统, 能将真正配对的序列同随机产生的干扰序列区别开来;同时采 用启发式算法系统,即采用的是局部对准算法( Local Alignment Algorithm),而不是全序列对准算法( Global Alignment Algorithm) ◆ Blast是通过比对( alignment)在数据库中寻找和你的查询序列 ( query)相似度很高的序列。通俗地说就是在已知的序列数据库 中找和你的序列差不多的序列
◆ BLAST (Basic Local Alignment Search Tool)即碱基局部对准检索 工具,是一种序列类似性检索工具。它采用统计学记分系统, 能将真正配对的序列同随机产生的干扰序列区别开来;同时采 用启发式算法系统,即采用的是局部对准算法(Local Alignment Algorithm),而不是全序列对准算法(Global Alignment Algorithm)。 ◆ Blast是通过比对(alignment)在数据库中寻找和你的查询序列 (query)相似度很高的序列。通俗地说就是在已知的序列数据库 中找和你的序列差不多的序列。 12
>http://www.ncbi.nim.nihgov/ NCBI Resources回 How To Sign in to NCBI NCBI All Databases Search Biotechn Welcome to ncbl Popular Resources Resource List(A-z) The National Center for Biotechnology Information advances science and health by providing access to PubMed All Resources biomedical and genomic information Bookshelf Chemicals& Bioassays About the NCB! I Mission I Organization I NCBI News I Blog bMed Central Data& Software dnA RNA earn BLAST Domains& structures Deposit data or manus Transfer NCBI data to your Find help documents, attend a Nucleotide Genes & Expres nto NcBl databases class or watch a tutorial Genome Genetics Medicine Genomes& Maps Gene Protein Homology PubChem Literature Proteins Sequence Analysis Develop NCBI Announcements Analyze Research Use NcBl APls and code Identify an NCBI tool for your Explore NCBI research and December 17th webinar. Accessing Training & Tutorials libraries to build applications data analysis task collaborative projects 1000 Genomes Project Data 03Dec2015 Variation On Thursday December 17th, 2015, NCBI staff wall demonstrate how to arce Registration open for December 16th NCBI Minute: "New Faceted Advanced Search in dbGaP Provides Easy Access
➢http://www.ncbi.nlm.nih.gov/ 13
>http://blast.ncbi.nim.nihgov/blast.cgi Basic Local Allgnment Search Tool Web BLAST Protein BLAS Stand atona and Ap BLAST
➢http://blast.ncbi.nlm.nih.gov/Blast.cgi 14
Basic Local Alignment search tool N BLAST+2.4.0 released BLAST finds regions of similarity between biological sequences. The program E Anew version (2.4.0)of the BLAST+ executables is now available. compares nucleotide or protein sequences to sequence databases and W Thu, 02 Jun 2016 14: 00: 00 EST a More blast news calculates the statistical significance Learn more Web BlAst blast translated nucleotide > protein Nucleotide blast tblastn Protein BLAST nucleotide > nucleotide protein b translated nucleotide protein protein BLAST Genomes Enter organism common name, scientific name, or tox id Search Humal Mouse Microbes
15