MENOPAUSE 1. The cessation of menses is menopause. The climacteric and perimenopausal are the periods of waning ovarian function
MENOPAUSE • 1.The cessation of menses is menopause.The climacteric and perimcnopausal are the periods of waning ovarian function
90 90 2.Female life expectancY 80 80 70 70 60 50 50 Age of menopause 40 850 1900 1950 2000 Age of menopause and female life expectancy
Age of menopause Age of menopause and female life expectancy. 2.Female life expectancy 1850 1900 1950 2000 40 50 60 70 80 90 90 80 70 60 50 40
3SYMPTOMS AND SIGNS OF OVARIAN FAILURE (1) Menstrual Cycle Alterations Soon after an adolescentwoman has her first menstrual cycle, regular, predictable menstrual cycles are established that continue until approximately 40 years of age. Around 40 years the number of ovarian follicles becomes substantially depleted and subtle changes occur in the frequency and length of menstrual cycles
3.SYMPTOMS AND SIGNS OF OVARIAN FAILURE (1) Menstrual Cycle Alterations Soon after an adolescentwoman has her first menstrual cycle, regular, predictable menstrual cycles are established that continue until approximately 40 years of age. Around 40 years, the number of ovarian follicles becomes substantially depleted and subtle changes occur in the frequency and length of menstrual cycles
A woman may note shortening or lengthening of her cycles. The luteal phase of the cycle remains constant at 13 to 14 days. whereas the variation of cycle length is related to a change in the follicular phase Women in their 20s and 30s ovulate 13 to 14 times per year. Several years in advance of menopause, the frequency of ovulation decreases to ll to 12times per year and with advancing reproductive age, may decrease to 3 to 4 times per year
• A woman may note shortening or lengthening of her cycles. The luteal phase of the cycle remains constant at 13 to 14 days, whereas the variation of cycle length is related to a change in the follicular phase. Women in their 20s and 30s ovulate 13 to 14 times per year. Several years in advance of menopause, the frequency of ovulation decreases to 11 to 12times per year and, with advancing reproductive age, may decrease to 3 to 4 times per year
With the change in reproductive cycle length and frequency there are concomitant changes in the plasma concentration of fsh andl. more FSH is required to stimulate follicular maturation. Beginning in the late 30s and early 40s, the concentration of FSH begins to increase. This is the frist chemical evidence of ovarain failure
• With the change in reproductive cycle length and frequency ,there are concomitant changes in the plasma concentration of FSH and LH . More FSH is required to stimulate follicular maturation .Beginning in the late 30s and early 40s, the concentration of FSH begins to increase . This is the frist chemical evidence of ovarain failure