Lab investigations MBBS project, Zhongshan Hospital
MBBS project, Zhongshan Hospital Lab investigations
Spirometry Objective indices for airflow limitation ° Reproducibility Important for diagnosis, assessment of the severity of the disease, disease progression monitoring, assessment of prognosis, and M response to therapy Indices for airflow obstruction (1)FEV,% predicted (2)FEV,/FVC MBBS project, Zhongshan Hospital
MBBS project, Zhongshan Hospital Spirometry • Objective indices for airflow limitation • Reproducibility • Important for diagnosis, assessment of the severity of the disease, disease progression monitoring, assessment of prognosis, and response to therapy • Indices for airflow obstruction: （1）FEV1% predicted （2）FEV1 /FVC
Spirometry(Cont'd) FEV/ FVC9O sensitive, capable of detection for mild airflow obstruction FEV,% predicted good indicator for moderate-severe airflow obstruction Airflow obstruction is confirmed by post bronchodilator Fev vc<0.7 MBBS project, Zhongshan Hospital
MBBS project, Zhongshan Hospital Spirometry (Cont’d) • FEV1／FVC% — sensitive, capable of detection for mild airflow obstruction • FEV1% predicted — good indicator for moderate-severe airflow obstruction • Airflow obstruction is confirmed by postbronchodilator FEV1／FVC＜0.7
Chest X-ray Objective To rule out alternative diagnosis such as tuberculosis and fibrosis, and identify complications In early stage of coPd Usually no abnormalities In late stage of coPd Always non-specific MBBS project, Zhongshan Hospital
MBBS project, Zhongshan Hospital Chest X-ray • Objective — To rule out alternative diagnosis such as tuberculosis and fibrosis, and identify complications • In early stage of COPD — Usually no abnormalities • In late stage of COPD — Always non-specific
Advanced Emphysema Large volume lungs Thin heart shadow Flattened hemidiaphragms Attenuated vascular markings in the upper lobe MBBS project, Zhongshan Hospital
MBBS project, Zhongshan Hospital Advanced Emphysema • Large volume lungs • Thin heart shadow • Flattened hemidiaphragms • Attenuated vascular markings in the upper lobe