NH2 NH H2O- +HoCH, Ch,N(C,Hs),+ HCl COOHCH2CHaN(C2H5)2HCI COOH 盐酸普鲁卡因 I2N SO2NH2 百浪多息 SO2NH?
H2N N2H N N SO2NH2 H2N NH2 NH2 + NH2 SO2NH2 NH2 COOHCH2CH2N(C2H5)2HCl + H2O NH2 COOH +HOCH2CH2N(C2H5 )2 + HCl 盐酸普鲁卡因 百浪多息
CH CH N CH3 CH3 氯丙嗪 CH3 HO Cl Cl CH CH
N S N CH3 CH3 CI O N S N CH3 CH3 CI N S N CH3 CH3 CI N S N CH3 CH3 CI N S N H CH3 CI HO O 氯丙嗪
NHCOCH3 NHCOCH3 OCh 5 OH 非那西丁 扑热息痛
OC2 H5 NHCOCH3 OH NHCOCH3 非那西丁 扑热息痛
o NH COOH N CH 3 N COOH H CH CH H2N H3C 异烟肼体内主要代谢途径
N N H NH2 O N COOH N N H H N O CH3 O H2N H N CH3 O N H H N CH3 O H3C O N N H COOH O 异烟肼体内主要代谢途径
Introduction 2. Drug metabolism and effect: 失活( pharmacological deactivation或降低 活化( pharmacological actiⅳ vation)或增强 产生毒性代谢物( toxication)或作用改变
2.Drug metabolism and effect： 失活(pharmacological deactivation)或降低 活化(pharmacological activation)或增强 产生毒性代谢物(toxication)或作用改变 ▪ Introduction