Otosclerosis Chunfu dai Otolaryngology Department Fudan University
Otosclerosis Chunfu Dai Otolaryngology Department Fudan University
Background Definition primary metabolic bone disease of the otic capsule and ossicles It causes fixation of the ossicles(stapes u It results in conductive or mixed hearing loss It is genetically-mediated via autosomal dominant transmission
Background ◼ Definition ◼ primary metabolic bone disease of the otic capsule and ossicles ◼ It causes fixation of the ossicles (stapes) ◼ It results in conductive or mixed hearing loss. ◼ It is genetically-mediated via autosomal dominant transmission
Epidemiology Ra ace incidence of microscopic otosclerosis Caucasian 10% Asian 5% African american 1% Native american 0
Epidemiology Race incidence of microscopic otosclerosis Caucasian 10% Asian 5% African American 1% Native American 0%
Epidemiology Sex variation(M: F=1: 2.5) u Women more commonly seek medical attention for hearing loss secondary to otosclerosis histologic studies prevalence of otosclerosis show no difference in men versus women
Epidemiology ◼ Sex variation (M:F=1:2.5) ◼ Women more commonly seek medical attention for hearing loss secondary to otosclerosis, ◼ histologic studies prevalence of otosclerosis show no difference in men versus women
Epidemiology Age The incidence of otosclerosis increases with age. u The most common age group presenting with hearing loss from otosclerosis is 15-45 years, s however it has been reported to manifest as early as 7 years and as late as the mid 50s
Epidemiology ◼ Age ◼ The incidence of otosclerosis increases with age. ◼ The most common age group presenting with hearing loss from otosclerosis is 15-45 years, ◼ however it has been reported to manifest as early as 7 years and as late as the mid 50s