Glomus jugular tumor Chunfu dai m,d ph. d
Glomus jugular tumor Chunfu Dai M.D & Ph.D
Background Originate from chemoreceptor jugular vein a glomus jugulare tumor is arisen in the adventitia of the dome of the jugular bulb This tumor is part of the neuroendocrine system, these tumors are highly vascularized Glomus tumors represent 0.6% of neoplasms of the head and neck
Background ◼ Originate from chemoreceptor jugular vein ◼ glomus jugulare tumor is arisen in the adventitia of the dome of the jugular bulb ◼ This tumor is part of the neuroendocrine system, these tumors are highly vascularized. ◼ Glomus tumors represent 0.6% of neoplasms of the head and neck
Pathology J All paraganglia are composed of chief cells (type I cells, ie, chemoreceptive cells)and sustentacular cells(type l cells, ie, supporting cells). Developmentally, both types of cells are of neuroectodermal origin specifically, they arise from neural crest cells The vast majority of glomus tumors are benign and slow to grow with bone erosion
Pathology ◼ All paraganglia are composed of chief cells (type I cells, ie, chemoreceptive cells) and sustentacular cells (type II cells, ie, supporting cells). Developmentally, both types of cells are of neuroectodermal origin; specifically, they arise from neural crest cells ◼ The vast majority of glomus tumors are benign and slow to grow with bone erosion
Pathology Glomus jugulare tumors are typically located just under the skull base. at the bulb of the internal jugular vein. The tumors may spread superiorly into the jugular foramen, causing CN X, CN X and cn xi deficits The primary blood supply to jugulare tumors is via the ascending pharyngeal artery. In addition he occipital and posterior auricular arteries can contribute to vascularization Intraoperatively ligation of external carotid artery can significantly reduce the hemorrhage
Pathology ◼ Glomus jugulare tumors are typically located just under the skull base, at the bulb of the internal jugular vein. The tumors may spread superiorly into the jugular foramen, causing CN IX, CN X, and CN XI deficits. ◼ The primary blood supply to jugulare tumors is via the ascending pharyngeal artery. In addition, the occipital and posterior auricular arteries can contribute to vascularization. ◼ Intraoperatively ligation of external carotid artery can significantly reduce the hemorrhage
Symptoms Pulsatile tinnitus Conductive hearing loss, aural bleeding, and aural discharge Sensorineural hearing loss vertigo, aural pain and Cranial neuropathy. Such as it can compress CN X, X, and XI
Symptoms ◼ Pulsatile tinnitus, ◼ Conductive hearing loss, aural bleeding, and aural discharge. ◼ Sensorineural hearing loss, vertigo, aural pain and ◼ Cranial neuropathy. Such as it can compress CN IX, X, and XI. ◼