ORGAN OF CORTI Meniere’ s Disease Chunfu dai Otolaryngology Department Fudan University
Prevalence Incidence is 54 100000 in Japan 15/100000nUs,46/100000 n Sweden 100/100000inUK The large differences are due to geographic, genetic, ethnic or environmental factors or different diagnostic criteria
Background In1861, Meniere described a syndrome In1938, Hallpike and Yamakawa reported the finding of endolymphatic hydrops in temporal bone from patients with MD
Background In1972, AAOo report also defined two sub-varieties cochlear and vestibular mD In1985 AAO-HNS updated the term Md should be restrictive and include only those cases with complement of classic symptoms and findings of the disease presumed to result from idiopathic endolymphatic hydrops
Pathogenesis Radial circulation Longitudinal flow hair cells hair cells