The basal bodies of flagellum or cilium ★(9×3+0) 100nm This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more information
2.Microtubule-associated protein (MAP) (微管相关蛋白) MAPs modulate the structure,assembly,and function of MT: Bind with the surface of microtubules Participate in assembly of microtubules Types:MAP-1,MAP-2,tau,MAP-4. Differ on distribution and function. Tau:In axon,cause MTs to form tight bundles MAP2:In dendrites,cause MTs to form looser bundles MAP1B:In both axons and dendrites to form crossbridge between microtubules This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more information
Localization of MAPs in axon and dendrites of a neuron Distribution of Tau(green)and MAP-2(orange)in a hippocampal neuron in culture. 10um This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more information
The organization of microtubule bundles by MAPs microtubule microtubule tau MAP2 25 nm (A) (B) MTs (C) (D)】 300nm This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more information
The effects of proteins that bind to MT ends MAP RESULT: longer,less dynamic STABILIZATION microtubules frequency of catastrophes suppressed and/or growth rate enhanced GTP cap RESULT: on plus end DESTABILIZATION shorter,more of microtubule dynamic microtubules frequency of catastrophes catastrophe factor increased (kinesin 13) This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more information