T cells include several functionally distinct subtypes:T cytotoxic cell: produces perforin and other protein thatkill the tumor cell, virus infective cell and foreign cell:Thelper cell:promotes activity ofBLC andTc C;T memory cell:are long-lived, committed,immunocompetent cells, regulate the function of BLC andTC
T cells include several functionally distinct subtypes: T cytotoxic cell: produces perforin and other protein that kill the tumor cell, virus infective cell and foreign cell; T helper cell: promotes activity of BLC and Tc C; T memory cell: are long-lived, committed, immunocompetent cells, regulate the function of BLC and TC
b.B-lymphocytes,5%~10%,are primarilyresponsibleforhumoralimmunityTodifferentiateintoplasma cellsTo become memory cells that react to the same antigen insubsequentencountersc.NKcell(naturalkillercells)10%~15%,attackandlyseinvadingcells (virusinfective cellandtumor cell)throughdirectcell-cell contact, like T cytotoxic cells
b. B-lymphocytes , 5%~10%, are primarily responsible for humoral immunity To differentiate into plasma cells To become memory cells that react to the same antigen in subsequent encounters c. NK cell (natural killer cells) 10%~15%, attack and lyse invading cells (virus infective cell and tumor cell) through direct cell-cell contact, like T cytotoxic cells
Macrophagemononuclearphagocytic system③PlasmacellDAntigenPresentingCell:Dendritic cellDendritic cellLangerhans cell
② Macrophage mononuclear phagocytic system ③ Plasma cell ④Antigen Presenting Cell: Dendritic cell Langerhans cell Dendritic cell
Wandering LymphocytesAmeboidlymphocytespenetrate mostareas of thebody includingepithelia.EpithelialLymphocytes
Wandering Lymphocytes • Ameboid lymphocytes penetrate most areas of the body including epithelia. Epithelial Lymphocytes
Lymphoidtissue.--reticular T:reticular cell: stellate-shaped with processes to formnetworkreticular cellreticular fibermacrophage---immunocytes:(lymphocytes,lymphocytemacrophage,-reticularcell'sprocessesplasmacellplasma celland mast cell)reticularfiber
Lymphoid tissue -reticular T: reticular cell: stellate-shaped with processes to form network reticular fiber -immunocytes: (lymphocytes, macrophage, plasma cell and mast cell)