Syllabus forHistology&EmbryologySchool of Medicine,Yangzou UniversityTeaching SemesterThe 2nd SemesterStudentsSophomore (Six-year foreign student of Clinical Medicine)CreditsFive creditsCredit Hours96 hoursLecture Hours64 hoursLab Hours32 hoursSketchHistology & Embryology is composed of two related sciences. Histology focuseson microstructures of the human body and their related functions, and is divided intogeneral histology that studies the cell and intracellular matrix of the 4 basic types oftissue, and special histology that studies how the tissues constitute the organs invarious systems.While Embryology mainly concerns the developmental processesand mechanism of a human being, and is divided into general embryology that studiesthe formations and development of germ cells, fertilization and early development ofhuman embryo,and special embryology that studies theformation and malformationsof different organs. The teaching program of Histology & Embryology includeslectures and laboratory practices. The fast-developing Histology & Embryology is amain and fundamental course for different specialty of medicine,and makesthestudents to know the basic theory, knowledge and techniques, and acquire the ability1
1 Syllabus for Histology & Embryology School of Medicine, Yangzou University Teaching Semester The 2nd Semester Students Sophomore (Six-year foreign student of Clinical Medicine) Credits Five credits Credit Hours 96 hours Lecture Hours 64 hours Lab Hours 32 hours Sketch Histology & Embryology is composed of two related sciences. Histology focuses on microstructures of the human body and their related functions, and is divided into general histology that studies the cell and intracellular matrix of the 4 basic types of tissue, and special histology that studies how the tissues constitute the organs in various systems. While Embryology mainly concerns the developmental processes and mechanism of a human being, and is divided into general embryology that studies the formations and development of germ cells, fertilization and early development of human embryo, and special embryology that studies the formation and malformations of different organs. The teaching program of Histology & Embryology includes lectures and laboratory practices. The fast-developing Histology & Embryology is a main and fundamental course for different specialty of medicine, and makes the students to know the basic theory, knowledge and techniques, and acquire the ability
to analyzeand solveproblems infurther studies in othermedical courses and clinicmanagement.Teaching Modes1.PPT presentation2.Lab practice3. Online Platform (http://zzptx.yzuyxy.cn/en/)ExaminationModes1. Quizzes in class2. Final examinationTextbookThe Textbook of Histology and Embryology (Jicheng Li)Reference BooksI.Junqueira's Basic Histology:Text and Atlas, 13e (Anthony Mescher)2. Langman's Medical Embryology (Thomas W. Sadler)TeachingContentsandAllocationofCreditHoursUnitLecturePractice224Histology and Its Methods of Study42Epithelium314Connective tissue32Cartilage and bone31Bloodand Hematopoiesis32Muscular tissue441.5Nervous tissue20.5Skin224Circulatory system24Immunesystem424Endocrine system2
2 to analyze and solve problems in further studies in other medical courses and clinic management. Teaching Modes 1. PPT presentation 2. Lab practice 3. Online Platform (http://zzptx.yzuyxy.cn/en/) Examination Modes 1. Quizzes in class 2. Final examination Textbook The Textbook of Histology and Embryology (Jicheng Li) Reference Books 1. Junqueira's Basic Histology: Text and Atlas, 13e (Anthony Mescher) 2. Langman's Medical Embryology (Thomas W. Sadler) Teaching Contents and Allocation of Credit Hours Unit Lecture Practice Histology and Its Methods of Study 2 2 4 Epithelium 4 2 Connective tissue 3 1 4 Cartilage and bone 3 2 Blood and Hematopoiesis 3 1 Muscular tissue 3 2 Nervous tissue 4 1.5 4 Skin 2 0.5 Circulatory system 2 2 4 Immune system 4 2 Endocrine system 4 2 4
32Digestive tract324Digestive glands32Respiratorysystem314Urinary system31Male reproductive system32Female reproductive system4General embryology(Review and exam)42The Development of head, neck,andlimbs2The Development of the Digestive andRespiratory System2The Development of theUrogenitalSystem2The Developmentof theCardiovascularSystem64Total32m
3 Digestive tract 3 2 Digestive glands 3 2 4 Respiratory system 3 2 Urinary system 3 1 4 Male reproductive system 3 1 Female reproductive system 3 2 General embryology 4 (Review and exam) The Development of head, neck, and 4 limbs 2 The Development of the Digestive and Respiratory System 2 The Development of the Urogenital System 2 The Development of the Cardiovascular System 2 Total 64 32
Unit 1 Introduction to Histology (2h)Objectives1,Tomaster:Definition of Histology & Embryology,Hematoxylin and Eosin (H.E)staining method; basophilia and acidophilia; The resolution power of light andelectron microscopes; Length units (um, nm, A).2. To know: The progress and the research methods of histology; The observingmethods for living cells, histochemistry, cytochemistry and ultrastructure etc.Teaching contents1.Definition and contents of histology and embryology2.Relationship of histology and embryology to other medical courses3. Studying methoda.Lightmicroscopy:paraffin sectioning and H& E stainingb.Electronmicroscopyc. Histochemistry and cytochemistry: PAS reactiond.ImmunocytochemistryUnit2Epithelial Tissue (4h)Objectives1. To master: The structural characteristics, distribution and function of the epithelium,The structure, function and distribution of simple squamous epithelium (includingendothelium and mesothelium), simple cuboidal epithelium, simple columnarepithelium,pseudostratified columnar ciliated epithelium, stratified squamousepithelium and transitional epithelium; The specializations of the epithelium: thespecializations of the free surface (cilia and microvilli), lateral surface (junctionalcomplex); The structure of basal surface(basement membrane).Concept of theglandular epithelium and gland; Structural characteristics of the endocrine glandand exocrine gland.2. To know: Intercellular junctions (tight junction, desmosome, intermediate junctionand gap junction, The regeneration of the epithelium.4
4 Unit 1 Introduction to Histology (2h) Objectives 1. To master: Definition of Histology & Embryology; Hematoxylin and Eosin (H.E) staining method; basophilia and acidophilia; The resolution power of light and electron microscopes; Length units (um, nm, A). 2. To know: The progress and the research methods of histology; The observing methods for living cells, histochemistry, cytochemistry and ultrastructure etc. Teaching contents 1. Definition and contents of histology and embryology 2. Relationship of histology and embryology to other medical courses 3. Studying method a. Light microscopy: paraffin sectioning and H & E staining b. Electron microscopy c. Histochemistry and cytochemistry: PAS reaction d. Immunocytochemistry Unit 2 Epithelial Tissue (4h) Objectives 1. To master: The structural characteristics, distribution and function of the epithelium; The structure, function and distribution of simple squamous epithelium (including endothelium and mesothelium), simple cuboidal epithelium, simple columnar epithelium, pseudostratified columnar ciliated epithelium, stratified squamous epithelium and transitional epithelium; The specializations of the epithelium: the specializations of the free surface (cilia and microvilli), lateral surface (junctional complex); The structure of basal surface(basement membrane). Concept of the glandular epithelium and gland; Structural characteristics of the endocrine gland and exocrine gland. 2. To know: Intercellular junctions (tight junction, desmosome, intermediate junction and gap junction; The regeneration of the epithelium
Teaching contents1. Classification and general features of the epithelial tissues2. Covering epithelia: type, distribution, and function3.Epithelial specializationsa. Free surface: microvilli, ciliab. Lateral surface: cell junctionsc.Basal surface:basement membrane, plasma membrane infolding,hemidesmosome.4. Glandular epithelia and glands5.Renewal ofepitheliaUnit 3ConnectiveTissue (3h)Objectives1, To master: The structural characteristics and classification of the connective tissue.Concept of mesenchyme;The structural characteristic and function of looseconnective tissue; The chemical constituents, morphological structure andfunction of 3 fiber types (collagenous, elastic and reticular fibers); The chemicalconstituents and characteristics of the matrix of intercellular substance:Thestructure and function of several main cell types in connective tissue (fibroblastmacrophage, plasma cell, mast cell, fat cell and mesenchymal cell)2.To know:The structural characteristics and function of dense connective tissue,adipose tissue, reticular tissue and the tissue fluid.Teaching contents1. Classification and general characteristics of connective tissue2. Loose connective tissuea. Cells: structures and functions of fibroblasts, macrophages, plasma cells, mastcells; fat cells, mesenchymal cells and leukocytes.b.Fibers:morphology and function of collagenousfibers, elastic fibers, andreticular fibers.5
5 Teaching contents 1. Classification and general features of the epithelial tissues 2. Covering epithelia: type, distribution, and function 3. Epithelial specializations a. Free surface: microvilli, cilia b. Lateral surface: cell junctions c. Basal surface: basement membrane, plasma membrane infolding, hemidesmosome. 4. Glandular epithelia and glands 5. Renewal of epithelia Unit 3 Connective Tissue (3h) Objectives 1. To master: The structural characteristics and classification of the connective tissue. Concept of mesenchyme; The structural characteristic and function of loose connective tissue; The chemical constituents, morphological structure and function of 3 fiber types (collagenous, elastic and reticular fibers); The chemical constituents and characteristics of the matrix of intercellular substance; The structure and function of several main cell types in connective tissue (fibroblast, macrophage, plasma cell, mast cell, fat cell and mesenchymal cell). 2. To know: The structural characteristics and function of dense connective tissue, adipose tissue, reticular tissue and the tissue fluid. Teaching contents 1. Classification and general characteristics of connective tissue 2. Loose connective tissue a. Cells: structures and functions of fibroblasts, macrophages, plasma cells, mast cells; fat cells, mesenchymal cells and leukocytes. b. Fibers: morphology and function of collagenous fibers, elastic fibers, and reticular fibers