Alimentary tract:Imilkless; contaminatedby bovine type3Local skin lesion:rare
② Alimentary tract: less; contaminated milk by bovine type ③ Local skin lesion: rare
2. Pathogenic substance ofmycobacterium tuberculosis① Lipid:i Related to pathogenicity, especially glycolipiddestroythemembranecord factor:ofmitochondriainhibittheemigration ofleukocyterelatedtotheformationofgranulomaD: cause severe allergy→ tissue damagewax
2. Pathogenic substance of mycobacterium tuberculosis ① Lipid: ⅰ Related to pathogenicity, especially glycolipid cord factor: wax D: cause severe allergy→ tissue damage ◆ destroy the membrane of mitochondria ◆ inhibit the emigration of leukocyte ◆ related to the formation of granuloma
ii Protect bacillary bodiessfromdigestion of macrophageinhibit bacteria combine withlysosome, the bacteria can surviveii Phosphatidechange the macrophage into epithelioidcells in the inflammatory focus
ⅱ Protect bacillary bodies from digestion of macrophage inhibit bacteria combine with lysosome, the bacteria can survive ⅲ Phosphatide change the macrophage into epithelioid cells in the inflammatory focus
Polysaccharidelipoarabinomannaninhibitactivity of macrophagesecretingTNF-a: necrosisIL-10: inhibit celimmune
② Polysaccharide lipoarabinomannan inhibit activity of macrophage secreting TNF-α: necrosis IL-10: inhibit cell immune
Complement:3Promoting phagocytosisProtein:Heat-shock protein4Ag - autoinmmune reaction
③ Complement: Promoting phagocytosis ④ Protein:Heat-shock protein Ag autoinmmune reaction