The characteristic lesion Formation of tubercleCentral caseous necrosis
The characteristic lesion : ▪ Formation of tubercle ▪ Central caseous necrosis
2. ClassificationTBPulmonaryprimary TBsecondaryTBExtra pulmonary TBCintestinal TBtuberculous meningitistuberculous peritonitisTB of bone,jointTB ofLNTB ofurinary SgenitalS
2. Classification Pulmonary TB primary TB secondary TB Extra pulmonary TB intestinal TB tuberculous meningitis tuberculous peritonitis TB of bone , joint TB of LN TB of urinary S genital S
二. Etiology and Pathogenesis1. The pathogenic organismG+Mycobacterium TBTuberclebacillus(1) Type:M. hominidmainlyresponsibleforM.bovinedisease in manMouse, fish type-→have no virulence in host
二. Etiology and Pathogenesis 1. The pathogenic organism Mycobacterium TB G+ Tubercle bacillus (1) Type: M. hominid M. bovine Mouse, fish type→have no virulence in host mainly responsible for disease in man
Routesofinfection(2) Respiratory tract: maindirect personntopersontransmission of sneeze,cough droplets withorganisms(1-20 bacteria droplet)
(2) Routes of infection ① Respiratory tract: main direct person to person transmission of sneeze, cough droplets with organisms(1-20 bacteria / droplet)