丿 brio o dolere gastrone ritis Vibrio pard hemd icus--gastroenteritis oundinfectio, cteremia Vibrio vulnificus -Wound infection, bacteremia
Vibrio • Vibrio cholerae --gastroenteritis • Vibrio parahaemolyticus -- gastroenteritis, wound infection, bacteremia • Vibrio vulnificus -- wound infection, bacteremia
V cholerae Grows in salt and fresh water Endemic in areas of poor sanitation(India and Bangladesh ) transmitted by fecal-oral route Can survive and multiply in brackish water by infecting copepods Has over 150 identified serotypes based on O-antigen Only ol and o139 are toxigenic and cause Cholera disease
➢ Grows in salt and fresh water ➢ Endemic in areas of poor sanitation (India and Bangladesh ), transmitted by fecal-oral route ➢ Can survive and multiply in brackish water by infecting copepods ➢ Has over 150 identified serotypes based on O-antigen ➢ Only O1 and O139 are toxigenic and cause Cholera disease V. cholerae
Classification: O1 Antigen Biotype EI Tor Classical Serotype Ogawa Inaba Hikojima Ogawa (Hikojima Antigens A B A C (A,B,C)A,B A, C (A, B, C) 小川型稻叶型彦岛型
Classification: O1 Antigen 小川型 稻叶型 彦岛型
Classification: Other antigens >o139 Serogrou In 1993, an entirely new serogroup(0139)cause an epidemic in Bangladesh 0139 organisms produce a polysaccharide capsule but do not produce O1 LPS or Ol antigen Non-O1, Non-O139 Serogroup Most are ct(cholera toxin) negative and are not associated with epidemic disease
Classification: Other antigens ➢ O139 Serogroup In 1993, an entirely new serogroup (O139) cause an epidemic in Bangladesh. O139 organisms produce a polysaccharide capsule but do not produce O1 LPS or O1 antigen. ➢ Non-O1, Non-O139 Serogroup Most are CT (cholera toxin) negative and are not associated with epidemic disease
Profile of vibrio cholerae G, curved or comma-shaped rods Highly motile, polar flagellum Sensitive to low pH and die rapidly in solutions below ph 6 Proliferate in summers · Cholera toxin Pathogenic and nonpathogenic strains 206 serogroups
Profile of vibrio cholerae • G-, curved or comma-shaped rods • Highly motile; polar flagellum • Sensitive to low pH and die rapidly in solutions below pH 6 • Proliferate in summers • Cholera toxin • Pathogenic and nonpathogenic strains • 206 serogroups