This method is particularly useful in (a)determining whether a correlation exists between in vitro and in vivo bioavailability for immediate-release roducts (b)assessing the integrity and transit time of enteric coated tablets through the stomach en route to the intestines (c)drug and dosage form evaluation in new product development
This method is particularly useful in (a)determining whether a correlation exists between in vitro and in vivo bioavailability for immediate-release products, (b)assessing the integrity and transit time of enteric coated tablets through the stomach en route to the intestines, (c)drug and dosage form evaluation in new product development
1) The manufacture of hard gelatin capsule shells Hard gelatin capsule shells are manufactured in two sections the capsule body and a shorter cap The shells are produced industrially by the mechanical dipping of pins or pegs of the desired shape and diameter into temperature-controlled reservoir of melted gelatin mixture
1) The manufacture of hard gelatin capsule shells • Hard gelatin capsule shells are manufactured in two sections, the capsule body and a shorter cap. • The shells are produced industrially by the mechanical dipping of pins or pegs of the desired shape and diameter into a temperature-controlled reservoir of melted gelatin mixture
超 CONI SNAP
The pegs submerged to the desired depth and maintained for the desired period to achieve the proper length and thickness of coating The pegs are slowly lifted from the bath and the gelatin dried by a gentle flow of temperature- and humidity-controlled air When dried, each capsule part trimmed mechanically to the proper length and removed from the pegs and the capsule bodies and caps are joined together
• The pegs submerged to the desired depth and maintained for the desired period to achieve the proper length and thickness of coating. • The pegs are slowly lifted from the bath and the gelatin dried by a gentle flow of temperature- and humidity-controlled air. • When dried, each capsule part trimmed mechanically to the proper length and removed from the pegs, and the capsule bodies and caps are joined together
空胶囊的制备工艺 溶胶蘸胶干燥拔壳切割 整理 般由自动化生产线完成,生产环境洁 净度应达10000级,温度10~25C,相 对湿度35~45%
空胶囊的制备工艺： • 溶胶 蘸胶 干燥 拔壳 切割 整理 • 一般由自动化生产线完成，生产环境洁 净度应达10000级，温度1025C，相 对湿度3545%