2.New drugs:new drugs are the drugs that are not posted in state pharmacopoeia()or approved to be used by the state department of pharmaceutical administration. (National Medical Products Administration,NMPA) 国家药品监督管理局 National Medical Products Administration 中华人民共和国 药典 通想 木神机由 +中4aa。 2019/8/28 Institute of clinical pharmacology,AHMU 6
2.New drugs: new drugs are the drugs that are not posted in state pharmacopoeia(药典） or approved to be used by the state department of pharmaceutical administration. (National Medical Products Administration, NMPA) 2019/8/28 Institute of clinical pharmacology, AHMU 6
I Preclinical development of new drugs 2019/8/28 Institute of clinical pharmacology,AHMU
I Preclinical development of new drugs 2019/8/28 Institute of clinical pharmacology, AHMU 7
Preclinical development of new drug encompasses all of the activities that must take place before a new chemical entity can be administered to human. Lead Screening Cell lines and compound tests animal models Preclinical drug development Optimal drug candidate Clinical testing Human 2019/8/28 Institute of clinical pharmacology,AHMU 8
Lead compound Screening tests Cell lines and animal models Preclinical drug development Preclinical development of new drug encompasses（包 含） all of the activities that must take place before a new chemical entity can be administered to human. 2019/8/28 Institute of clinical pharmacology, AHMU 8 Optimal drug candidate Clinical testing development Human
Generally,preclinical drug development includes three areas (1)Vitro studies,药理学特性 (2)Drug supply and formulation (3)Vivo studies in animal models. 治疗原则证据和蘑在临床疗减 2019/8/28 Institute of clinical pharmacology,AHMU 9
Generally, preclinical drug development includes three areas ： (1) Vitro studies, 药理学特性 (2) Drug supply and formulation , (3) Vivo studies in animal models. 2019/8/28 Institute of clinical pharmacology, AHMU 9 治疗原则证据和潜在临床疗效
1.In Vitro Studies (1)Vitro screening assays are to study the ability of drugs: To bind to receptors, To inhibit specific enzymes, To stabilize or destabilize multi protein complexes. URP "Looks like Carstairs finally got a single cell to eat a whole meal By the way,have you seen Carstairs lately?" 2019/8/28 Institute of clinical pharmacology,AHMU 10
1. In Vitro Studies (1) Vitro screening assays are to study the ability of drugs: To bind to receptors, To inhibit specific enzymes, To stabilize or destabilize multi protein complexes. 2019/8/28 Institute of clinical pharmacology, AHMU 10