I.Structure organization and basic composition of plasma membrane 1.Membrane lipids -continuous double layer 磷脂(phospholipid) (1)甘油磷脂(phosphoglycerides) phosphatidylcholine(PC) phosphatidylserine(PS) phosphatidylethanolamine(PE) phosphatidylinositol (Pl) (2)鞘磷脂(sphingomyelin,SM) ■ 胆固醇(cholesterol) 糖脂(glycolipid) This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more information
☆Amphipathic molecule(双亲性分子) Molecule has both hydrophilic(亲水性)and hydrophobic(疏水性)parts. shape of lipid packing of lipid molecule molecules lipid micelle wate lipid bilayer (A) (B) Packing arrangements of lipid molecules in an aqueous environment. This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more information
Lipids:amphipathic molecules(双亲性分子) Polar end Choline (hydrophilic) （亲水性) 0 CH2-CH-CH2 Glycerol 0 0 c-0 C=O Nonpolar end (hydrophobic) (疏水性) This document is produced by trial version of Print2Flash.Visit www.printflash.com for more information
1.1 Phospholipids(磷脂) H2一NCHh CHOLINE polar (hydrophilic) PHOSPHATE head group GLYCEROL hydrophilic head =0 0 hydrophobic 1 2 tails (D) nonpolar cis-double (hydrophobic) bond tails HYDROCARBON TAIL HYDROCARBON TAIL c (A) (B) (C) This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more information
Lipids Bilayer Basic structure of plasma membrane. ENERGETICALLY UNFAVORABLE Serine Phosphate Hydrophilic heads interact with water planar phospholipid bilayer with edges exposed to water Hydrophobic tails interact with each other sealed compartment Hydrophilic heads interact with water formed by phospholipid bilayer ENERGETICALLY FAVORABLE The closed structure is stable because it avoids the exposure of the hydrophobic tails to water,which would be energetically unfavorable. This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more information