CLP were classified into syndrome type and non-syndrome type. Non-syndrome CLP(非综合征型唇腭裂)： It was not accompanied by other system malformations,did not belong to any syndrome
CLP were classified into syndrome type and non-syndrome type . Non-syndrome CLP(非综合征型唇腭裂): It was not accompanied by other system malformations, did not belong to any syndrome
Cleft lip and cleft palate may appear separately, or simultaneously. CLP will cause great impact on the appearance,language, swallowing function and even the psychology of patients and their families
• Cleft lip and cleft palate may appear separately, or simultaneously. • CLP will cause great impact on the appearance, language, swallowing function and even the psychology of patients and their families
2.Epidemiology(流行病学) Morbidity(发病率)：1/600~1000 (1)Racial difference(人种差异) The black race 0.2%0≈0.73%0； The white race: 1∞1.29%0； Asian: 1.18%02.128%0, Morbidity in China:1.625%0,increasing year by year
2. Epidemiology(流行病学) Morbidity（发病率）: 1/600～1000 （1）Racial difference（人种差异） The black race ： 0.2‰～0.73‰； The white race： 1～1.29‰； Asian： 1.18‰～2.128‰， Morbidity in China： 1.625‰, increasing year by year
(2)Gender(性别) Male:female 1.5:1;cleft palate,female more than male. 3 Season(季节) March to June;or winter;or related to the flu season. Occurrence Site(发生部位) Unilateral were more common,left>right>bilateral=6:3:1; Cleft lip and palate accounted for 50%, Cleft palate 30%,cleft lip 20%
（2）Gender（性别） Male：female ≈ 1.5∶ 1；cleft palate, female more than male. 3 Season（季节） March to June; or winter; or related to the flu season. 4 Occurrence Site（发生部位） Unilateral were more common, left＞right＞bilateral=6∶ 3∶ 1； Cleft lip and palate accounted for 50%， Cleft palate 30%，cleft lip 20%
5 Regional factors(地区因素) Rural >city=2~1.5:1 6 State of the economy（经济状况) The poor were common. Parents'age（妊娠年龄) The reproductive age of pregnant women was >35 years, and the risk was increased. 8 Familial(家族性) Those with family backgrounds accounted for 28%
5 Regional factors（地区因素） Rural ＞city = 2～1.5∶ 1 6 State of the economy（经济状况） The poor were common. 7 Parents‘ age（妊娠年龄） The reproductive age of pregnant women was >35 years, and the risk was increased. 8 Familial （家族性） Those with family backgrounds accounted for 28%