An ecological approach tomicrobes and diseaseLS-HHMI OutreachProgram Summer WorkshopHarvard UniversityCambridge,MAJuly 10, 2008JonClardy,HarvardUniversityjon_clardy@hms.harvard.edu
An ecological approach to microbes and disease LS-HHMI Outreach Program Summer Workshop Harvard University Cambridge, MA July 10, 2008 Jon Clardy, Harvard University jon_clardy@hms.harvard.edu
Central dogma andbiological information flowDNARNAprotein
Central dogma and biological information flow DNA RNA protein
Small molecules and biological information flowNH2HCthiamineserotoninP20gH3smallDNARNAproteinmoleculesOHHOtestosteronerapamycinOHOCHOHO=estradiolOHHCOCH
Small molecules and biological information flow DNA RNA protein small molecules testosterone thiamine serotonin estradiol rapamycin N N S O P2O6H3 NH2 + N H HO NH2 OH HO OH O OH OCH3 O OH OCH3 O OCH3 O O O O N HO
RolesofsmallmoleculesDyingloblollypinesDendroctonusfrontalisSouthernpinebeetle(SPB)ImagesfromKierKlepzig(USDA-FS)andhttp://www.dartmouth.edu/~mpayres/photos.htm
Dying loblolly pines Roles of small molecules Images from Kier Klepzig (USDA-FS) and http://www.dartmouth.edu/~mpayres/photos.htm Dendroctonus frontalis Southern pine beetle (SPB)
Southern pine beetle (Dendroctonus frontalis)rice grainsouthernpinebeetleblackturpentinebeetle
southern pine beetle rice grain black turpentine beetle Southern pine beetle (Dendroctonus frontalis)