Acute Rejection The most common type of transplant reiection Can be treated with chemotherapy It is mainly conducted by cell-mediated rejection in the early stage. However, antibody-mediated rejection also participate in the later stage
Acute Rejection The most common type of transplant rejection Can be treated with chemotherapy It is mainly conducted by cell-mediated rejection in the early stage. However, antibody-mediated rejection also participate in the later stage
> Cell-mediated rejection: (type Iv hypersensitivity ILA Stimulates CD4+, CD8 T lymphocytes. The morphologic characteristic is numerous mononuclear cells invasion in the tissue
➢Cell-mediated rejection: (type Ⅳ hypersensitivity ) HLA stimulates CD4+ 、CD8+T lymphocytes. The morphologic characteristic is numerous mononuclear cells invasion in the tissue
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>antibody-mediated rejection Also called as blood vessel type rejection. (type II hy vit persensitiv The morph hologic characteristic is fibrinoid necrosis of the blood vessel wall. immuno- fluorescence can prove there is immuno- complex precipitate in the necrosis tissue
➢antibody-mediated rejection: Also called as blood vessel type rejection. (type II hypersensitivity) The morphologic characteristic is fibrinoid necrosis of the blood vessel wall. Immunofluorescence can prove there is immunocomplex precipitate in the necrosis tissue
: 少翁