The Disease of Hematopoietic and Lymphoid Systems
The Disease of Hematopoietic and Lymphoid Systems
Hematopoietic and Lymphoid Systems a Myeloid tissue Bone marrow RBC, platelets, granulocytes, monocytes lymphoid tissue mph nodes lymus spl oleen
Hematopoietic and Lymphoid Systems ◼ Myeloid tissue ◼ Bone marrow ◼ RBC, platelets, granulocytes, monocytes ◼ Lymphoid tissue ◼ lymph nodes ◼ thymus ◼ spleen
Disorders a encompass a wide range of diseases, involving its any organs or tissues ■RBC: usually anemia WBC: overgrowth, usually malignant common and lethal
Disorders ◼ encompass a wide range of diseases, involving its any organs or tissues. ◼ RBC: usually anemia ◼ WBC: overgrowth, usually malignant common and lethal
Neoplastic proliferations of white cells Be defined briefly as follows Myeloid neoplasms髓样组织肿瘤 ymphoid neoplasms淋巴样组织肿瘤 3. Histiocytosis an-made classification The distinction in some cases may be blurred
Neoplastic proliferations of white cells Be defined briefly as follows: 1. Myeloid neoplasms 髓样组织肿瘤 2. Lymphoid neoplasms 淋巴样组织肿瘤 3. Histiocytosis Man-made classification The distinction in some cases may be blurred
Myeloid neoplasms Arise within hematopoietic stem cells Three general categories Acute myelogenous leukemia(AML急性髓性白血病 8 types: FAB classification MI-8 Chronic myeloproliferative disorders(慢性骨髓增生性疾病) Chronic myelogenous leukemia慢性髓性白血病 Polycythemia vera真性红细胞增生症 Myeloid metaplasia with myelofibrosis伴骨髓纤维化的髓样增生 Essential thrombocythemia真性血小板增生症 Myelodysplastic syndromes(骨髓增生异常综合症) Myeloid neoplasms: CD13, CD14, CD15CD64
Myeloid neoplasms ◼ Arise within hematopoietic stem cells ◼ Three general categories: ◼ Acute myelogenous leukemia (AML 急性髓性白血病) ◼ Chronic myeloproliferative disorders （慢性骨髓增生性疾病） ◼ Chronic myelogenous leukemia 慢性髓性白血病 ◼ Polycythemia vera 真性红细胞增生症 ◼ Myeloid metaplasia with myelofibrosis 伴骨髓纤维化的髓样增生 ◼ Essential thrombocythemia 真性血小板增生症 ◼ Myelodysplastic syndromes（骨髓增生异常综合症） Myeloid neoplasms: CD13,CD14,CD15,CD64 8 types: FAB classification M1~8