Molecular Diagnosis ll: Practical 张咸宁 zhangxianning@zju.edu.cn Tel:13105819271;88208367 Office: A705, Research Building 2012/09
Molecular Diagnosis II: Practical 张咸宁 zhangxianning@zju.edu.cn Tel：13105819271; 88208367 Office: A705, Research Building 2012/09
AREAS OF APPLICATION OF MOLECULAR DIAGNOSTICS Infectious disease Neoplastic Disease Genetic Disease Identity Testing HLA Typing Pharmacogenetics
Infectious Disease Neoplastic Disease Genetic Disease Identity Testing HLA Typing Pharmacogenetics AREAS OF APPLICATION OF MOLECULAR DIAGNOSTICS
APPLICATIONS OF MOLECULAR GENETIC TESTING Clinical diagnosis/confirmation Carrier screening ■ Prenatal diagnosis Presymptomatic/predisposition diagnosis
APPLICATIONS OF MOLECULAR GENETIC TESTING ◼ Clinical diagnosis/confirmation ◼ Carrier screening ◼ Prenatal diagnosis ◼ Presymptomatic/predisposition diagnosis
Resources GeneTestswww.genetests.org American College of Medical Genetics www.acmg.net National Society of Genetic Counselors www.nsgc.org Omim:http://www.ncbi.nlm.nih.gov/omim The journals: Molecular Diagnosis, Diagnostic Molecular Pathology, journal of molecular Diagnosis, Genetic Testing and molecular Biomarkers, Prenatal Diagnosis
Resources • Gene Tests: www.genetests.org • American College of Medical Genetics: www.acmg.net • National Society of Genetic Counselors: www.nsgc.org • OMIM: http://www.ncbi.nlm.nih.gov/omim • The journals: Molecular Diagnosis, Diagnostic Molecular Pathology, Journal of Molecular Diagnosis, Genetic Testing and Molecular Biomarkers, Prenatal Diagnosis, …
Molecular genetic testing United states Testing used in patient care must be done in clinical" laboratories. not research laboratories Clinical laboratories have to meet standards set by federal law (Clia) Non-US laboratories are used when testing is not available in the us DETests
Molecular genetic testing: United States • Testing used in patient care must be done in “clinical” laboratories, not research laboratories • Clinical laboratories have to meet standards set by federal law (“CLIA”) • Non-US laboratories are used when testing is not available in the US