Anatomy physiology feely Huan ma(马欢),PhD Department of physiology Room 515. block c. Research building School of Medicine, Zijingang Campus Email:mah@zju.edu.cn Tel:88208068
Anatomy & physiology of cells Huan Ma（马欢），PhD Department of Physiology Room 515, Block C, Research Building School of Medicine, Zijingang Campus Email: mah@zju.edu.cn Tel: 88208068
Sectional view Figure 3-1 Anatomy and Physiology: From Science to Life 9 2006 John Wiley Sons
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Structure of cell membrane Fluid Mosaic Model(Singer Nicholson, 1972) Proteins Carbohydrate Lipids 6
Structure of cell membrane: Fluid Mosaic Model (Singer & Nicholson, 1972)
Compartment 1 Compartment 2 High solute concentration Low solute concentration One-way flux∴∴∴∵ One-way flux Net flux Note: the partition between the two com partments is a membrane that allows this solute to move through it. Net flux accounts for solute movements in both directions
Note: the partition between the two compartments is a membrane that allows this solute to move through it. Net flux accounts for solute movements in both directions
Simple Diffusion单纯扩散 Relative to the concentration gradient movement is down the concentration gradient ONLY (higher concentration to lower concentration) (outside) lipid- soluble molecules Rate of diffusion depends on O2, CO2, H2O The concentration gradient Charge on the molecule Size Lipid solubility 0888 ° Temperature (inside)
Simple Diffusion 单纯扩散 Relative to the concentration gradient movement is DOWN the concentration gradient ONLY (higher concentration to lower concentration) Rate of diffusion depends on • The concentration gradient • Charge on the molecule • Size • Lipid solubility • Temperature