(3)Lipid free radicals; The interaction of oxygen free radicals with polyunsaturated fatty acids in the phospholipids of cell membrane leads to the formation of lipid free radicals Types 1) Fatty acid radical (lL 2)Lipid peroxide (LOO) (4)Others: Cl, CH3 NO
(3) Lipid free radicals： The interaction of oxygen free radicals with polyunsaturated fatty acids in the phospholipids of cell membrane leads to the formation of lipid free radicals. Types： 1) Fatty acid radical (L·) 2) Lipid peroxide（LOO·） (4) Others: Cl·, CH3·, NO·
(5)Generation and elimination of oxygen free radicals 1)Origin of"2: a mitochondria b. Oxidation of some chemicals in body. C Catalysis by enzymes d stimulation of cells with toxins
(5) Generation and elimination of oxygen free radicals 1) Origin of O·- 2： a. Mitochondria b. Oxidation of some chemicals in body. c. Catalysis by enzymes d. Stimulation of cells with toxins
(6)Generation of OFR 02+8 02+28+2H+ byte n2+38+3H+-H0+l H202 02+4+4H+—2出20 SOD, Superoxide dismutase
(6) Generation of OFR O2 + e O2 • O2+ 2e + 2H+ H2O2 H2O2 O2 + 3 e + 3H+ HO• +H2O O2 + 4 e + 4H+ 2 H2O Cytaa3 SOD SOD, Superoxide dismutase
Haber-Weiss reaction(without Fe+3 2·+20202+0H+0H SLOW hydroxyl radical; ferrum
Haber-Weiss reaction (without Fe+3 ) O2 －• + H2O2 O2 + OH +OH• SLOW hydroxyl radical; ferrum