250 出血性疾病 Hemorrhagic disorder 珠江医院血液科邓兰2020.4
Key words ·Hemorrhage,hemorrhagic出血,& 出血的 Hemostasis,hemostatic 止血,止血的 ·Blood coagulation 凝血 Fibrinolysis,fibrinolytic 纤溶,纤溶的
Contents ·Summary ·Allergic purpura Immune thrombocytopenia Thrombotic thrombocytopenic purpura ·Hemophilia
Chapter 1 --Summary
Factors of hemostasis 1.Blood vessel 2.Platelet --When it is injured its endothellal cells will release · By VWF,platelets adhere to VWF to make platelets adhere collagen fiber to form thrombus and aggregate there of platelets release TF to start extrinsic pathway of coagulation By fibrinogen,platelets aggregate collagen fiber of blood vessel exposed will activate FXIl,and Then the platelets activated start intrinsic pathway of excrete substance to regulate coagulation blood coagulation 血小板 GPI。-IX 纤维 WF 胶原 GPII。-a 蛋白原 血小板聚集