28.2 Transforming viruses carry Viral infection oncogenes Viral genes enter germline Figure 28.6 Retroviruses transfer genetic information horizontally by infecting new hosts; All cells of information is inherited progery carry vertically if a virus endogenous virus integrates in the genome of the germline. 清菜大当
Figure 28.6 Retroviruses transfer genetic information horizontally by infecting new hosts; information is inherited vertically if a virus integrates in the genome of the germline. 28.2 Transforming viruses carry oncogenes
RNA 28.2 Transforming Reverse viruses carry transcription LTR LTR oncogenes Linear DNA NA入NNNN Figure 16.2 The retroviral Integration Circul arization life cycle proceeds by reverse transcribing the RNA genome into duplex DNA,which is inserted Provirus N八入ZVD20702021702 into the host genome,in order to be transcribed into Transcription RNA RNA 清第大当
Figure 16.2 The retroviral life cycle proceeds by reverse transcribing the RNA genome into duplex DNA, which is inserted into the host genome, in order to be transcribed into RNA. 28.2 Transforming viruses carry oncogenes
28.2 Transforming viruses carry oncogenes Original virus RU5 gag pof env Figure 28.7A transforming retrovirus carries a Transforming virus copy of a cellular RU5 gag v-onc sequence in place of some of its own Copy of spliced cellular gene gene(s) 清菜大学 Gag-Onc fusion protein
Figure 28.7 A transforming retrovirus carries a copy of a cellular sequence in place of some of its own gene(s). 28.2 Transforming viruses carry oncogenes
28.3 Retroviral oncogenes have cellular counterparts Proto-oncogenes are the normal counterparts in the eukaryotic genome to the oncogenes carried by some retroviruses.They are given names of the form c-onc. 清菜大当
Proto-oncogenes are the normal counterparts in the eukaryotic genome to the oncogenes carried by some retroviruses. They are given names of the form c-onc . 28.3 Retroviral oncogenes have cellular counterparts
28.3 Retroviral oncogenes have cellular counterparts Virus Name Species Tumor Oncogene Rous sarcoma RSV chicken sarcoma sre Harvey murine sarcoma Ha-MuSV rat sarcoma erythroleukemia H-as Kirsten murine sarcom a KiMuSV rat sarcoma erythroleukemia X-怕s Moloney murine sarcomaMo-MuSV mouse sarcoma mos FBJ murine osteosarcomBJ-MuSV m ouse chondrosarcom a fos Simian sarcoma SSV m onkey sarcoma sis Feline sarcoma PI-FeSV cat sarcoma sis Feline sarcoma SM-FeSV cat fbrosarooma fms Feline sarcoma ST-FeSV cat fibrosarcoma fes AMan sarcoma ASV-17 chicken fbrosarcoma jun Fujinami saroom a FuSV chicken sarcoma f的s Avian m yelocytomatosis MC29 chicken carcinom a,sarcoma,m yelocytonye Abelson leukemia MuLV m ouse B cell lymphoma abl Reticuloendotheliosis REV-T turkey lym phatic leukemia ref Avan erythroblastosis E√ chicken erythroleukemia fibrosarcom a ebB,ebA Avian m yeloblastosis V chicken m yeloblastic leukemia myb Figure 28.8 Each transforming retrovirus carries an oncogene derived from a cellular gene.Viruses have names and abbreviations reflecting the history of their isolation and the types of tumor they cause.This list shows some representative examples of the retroviral oncogenes 情華大当
Figure 28.8 Each transforming retrovirus carries an oncogene derived from a cellular gene. Viruses have names and abbreviations reflecting the history of their isolation and the types of tumor they cause. This list shows some representative examples of the retroviral oncogenes 28.3 Retroviral oncogenes have cellular counterparts