Respiratory Viruses
1 Respiratory viruses
Categories of Respiratory Viruses Orthomyxoviridae: Influenza virus Paramyxoviridae: Parainfluenza virus, Mumps virus; Measles, Respiratory syneytical virus Togaviridae: Rubella virus Coronaviridae: corona virus sais virus Adenoviridae humanAdenovirus picornaviridae: Rhino virus, Reoviridae:
2 Categories of Respiratory Viruses • Orthomyxoviridae: Influenza virus • Paramyxoviridae : Parainfluenza virus; Mumps virus; Measles; Respiratory syneytical virus • Togaviridae: Rubella Virus • Coronaviridae: Corona Virus; SARS virus • Adenoviridae : human Adenovirus • picornaviridae: Rhino Virus; • Reoviridae:
Influenza virus Orthomyxoviridae: Infuenza virus Influenza is a disease caused by Influenza virus a member of the Orthomyxoviridae
3 Influenza virus Orthomyxoviridae: Influenza virus Influenza is a disease caused by Influenza virus ,a member of the Orthomyxoviridae
Genome of Influenza virus 8 negative sense RNA nucleocapsid segments The RNP(RNA nucleoprotein) is in a helical form with the 3 polymerase polypeptides associated with each segment The segmented genome promotes genetic diversity caused by mutation and reassortment of segments on infection with two different strains
4 Genome of Influenza virus • 8 negative sense RNA nucleocapsid segments • The 'RNP' (RNA + nucleoprotein) is in a helical form with the 3 polymerase polypeptides associated with each segment. • The segmented genome promotes genetic diversity caused by mutation and reassortment of segments on infection with two different strains
Virion sphericallovoid 80 120nm diameter, The inner side of the envelope is lined by the matrix protein, stable type specIfIc
5 Virion • spherical/ovoid, 80 - 120nm diameter, • The inner side of the envelope is lined by the matrix protein, stable type - specific