Age dependent changes of serum Igs levels(g/L) Ages Igg IgA leM Neonate6.46-17740.004-0.0170.05-0.27 Im- 2.75-7.500.05-0.60 0.10-0.70 4m 3.70-8.300.140.50 0.33-125 7m 3.50-8.900.06-0.54 0.36-1.20 5.52-11.460.06-0.74 0.60-2.12 4.95-12.740.33-0.89 0.65-2.01 7 6.09-12.850.52-2.16 0.67-2.46 12 6.98-14260.92-2.50 0.56-2.18 15-18y7.54-16.020.89-3.24 0.72-228 Wang Xiaochuan Children's Hospital
Wang Xiaochuan Children’s Hospital Age dependent changes of serum Igs levels(g/L) Ages IgG IgA IgM Neonate 6.46-17.74 0.004-0.017 0.05-0.27 1m- 2.75-7.50 0.05-0.60 0.10-0.70 4m- 3.70-8.30 0.14-0.50 0.33-1.25 7m- 3.50-8.90 0.06-0.54 0.36-1.20 1y- 5.52-11.46 0.06-0.74 0.60-2.12 3y- 4.95-12.74 0.33-0.89 0.65-2.01 7y- 6.09-12.85 0.52-2.16 0.67-2.46 12y- 6.98-14.26 0.92-2.50 0.56-2.18 15-18y 7.54-16.02 0.89-3.24 0.72-2.28
Schematic diagram of the exposure of microorganism during early life pathogens probiotics fetus Full tern 6M Day care Wang Xiaochuan Children's Hospital
Wang Xiaochuan Children’s Hospital Schematic diagram of the exposure of microorganism during early life fetus Full tern 6M Day care pathogens probiotics
Period of susceptible children premature 6M Day care Full term Wang Xiaochuan Childrens Hospital
Wang Xiaochuan Children’s Hospital Period of susceptible children premature Full term 6M Day care
Management Exclusion of pid Clinical features Frequency of infection Severit Complications Follow up Wang Xiaochuan Childrens Hospital
Wang Xiaochuan Children’s Hospital Management • Exclusion of PID • Clinical features – Frequency of infection – Severity – Complications • Follow up
Management General medical care(prevention, nutrition exercise Complication Treatment Medication Antibiotics Immune regulator Immunizations Wang Xiaochuan Childrens Hospital
Wang Xiaochuan Children’s Hospital Management • General medical care (prevention、nutrition、 exercise) • Complication Treatment • Medication – Antibiotics – Immune regulator – Immunizations