Sepsis or septicemia in children
Sepsis or septicemia in children
Definition Bacteremia a Bacter ia invade into blood temporar i ly with flora <100 CFU/ mI in blood Septicemia or Seps is: Pathogens(bacter ia or fung i)invade into blood pro l iferate great ly, and release endotox in Toxemia Endotox in absor bed into b lood with no bacter ia Septicopyaemia: Sepsis with metastatic foci in or gans pyemia is a status which no bacter ium in blood is cultured
Definition Bacteremia： Bacteria invade into blood temporarily with flora <100 CFU/ml in blood Septicemia or Sepsis： Pathogens(bacteria or fungi) invade into blood,proliferate greatly,and release endotoxin Toxemia： Endotoxin absorbed into blood with no bacteria Septicopyemia： Sepsis with metastatic foci in organs,pyemia is a status which no bacterium in blood is cultured
Pathogens Gram stain positive coci Gram stain negative bacilli Anaerobic bacteria Fungi
Gram stain positive coci Gram stain negative bacilli Anaerobic bacteria Fungi Pathogens
Associated factors virulence and quantity Exotoxin. Endotoxin Defense mechanism Immunologic function, age, etc Chronical diseases Nephropathy, Liversclerosis, Connective tissue diseases, Diabetes mellitus, Malignant tumor, and so on Medical factors: long-term Steriods, Antibiotics, All kinds of instrumentation such as invasive meauver catheterization
virulence and quantity Exotoxin, Endotoxin Defense mechanism Immunologic function,age,etc Chronical diseases： Nephropathy,Liver sclerosis,Connective tissue diseases,Diabetes mellitus,Malignant tumor,and so on Medical factors： long-term Steriods,Antibiotics,All kinds of instrumentation such as invasive meauver,catheterization Associated factors
Polymicrobial sepsis More than one bacterium isolated in the same blood samples Associated with immunocompromised status Commonly occurs in patients with chronic diseases or use of immnodepressors
More than one bacterium isolated in the same blood samples Associated with immnocompromised status Commonly occurs in patients with chronic diseases or use of immnodepressors Polymicrobial sepsis