Macromolecule SynthesisWhen provided with building blocks and a source ofmetabolic energy, a cell synthesizes macromolecules The sequence of building blocks within a macromoleculeis determined in one of two ways In nucleic acids and proteins, it is template-directedDNA serves as the template forits own synthesis and for thesynthesis of the various types of RNAmessenger RNA serves as thetemplateforthesynthesis of proteinsIn carbohydrates and lipids, the arrangement of building blocks isdetermined entirely by enzyme specificitiesOnce the macromolecules have been synthesized, theyself-assemble to form the supramolecular structures of thecell, eg, ribosomes, membranes, cell wall, flagella andpiliSHIHEZIUNIVERSITY
Macromolecule Synthesis When provided with building blocks and a source of metabolic energy, a cell synthesizes macromolecules The sequence of building blocks within a macromolecule is determined in one of two ways In nucleic acids and proteins, it is template-directed DNA serves as the template for its own synthesis and for the synthesis of the various types of RNA messenger RNA serves as the template for the synthesis of proteins. In carbohydrates and lipids, the arrangement of building blocks is determined entirely by enzyme specificities Once the macromolecules have been synthesized, they self-assemble to form the supramolecular structures of the cell, eg, ribosomes, membranes, cell wall, flagella, and pili SHIHEZI UNIVERSITY
Metabolism RegulationThe rate of macromolecular synthesis andthe activity of metabolic pathways must beregulated so that biosynthesis is balancedSHIHEZI UNIVERSITY
Metabolism Regulation The rate of macromolecular synthesis and the activity of metabolic pathways must be regulated so that biosynthesis is balanced SHIHEZI UNIVERSITY