c.ComparativeEfficacy.MgSO4was showntobe superior to phenytoin in preventing seizuresin a recent trial. However, individualization ofphenytoin dosage, as recommended here, wasnot followed in that trial
c. Comparative Efficacy. MgSO4 was shown to be superior to phenytoin in preventing seizures in a recent trial. However, individualization of phenytoin dosage, as recommended here, was not followed in that trial
5.Conditions that necessitatedelivery,irrespectiveofgestational age, include the following:EclampsiaThrombocytopenia with a platelet level of less than100,000/mm3unless in setting of verymildly elevatedBPHemolysis (seen on peripheral blood smear)Elevated liverenzymelevelsPulmonaryedemaOliguriaPersistent need for antihypertensive medication
5. Conditions that necessitate delivery, irrespective of gestational age, include the following: Eclampsia Thrombocytopenia with a platelet level of less than 100,000/mm3 unless in setting of very mildly elevated BP Hemolysis (seen on peripheral blood smear) Elevated liver enzyme levels Pulmonary edema Oliguria Persistent need for antihypertensive medication
6.Antihypertensive therapy is indicated for antepartum,intrapartum,andpostpartumpatientswitha diastolicBP of105 mm Hg orhigher.Acute treatmentfor severe hypertensioninpregnancy involves reducing BPin a controlled mannerwithout reducing uteroplacental perfusion,which causes fetalheart rate decelerations.The goal is not to make the patientnormotensive but ratherto reduce thepatient's systolic BP to140to155mmHgandthediastolicBPto90to105mmHg.Ifunable to achieve the systolic range,more importance is placedonbringing down thediastolicvalue
6. Antihypertensive therapy is indicated for antepartum, intrapartum, and postpartum patients with a diastolic BP of 105 mm Hg or higher. Acute treatment for severe hypertension in pregnancy involves reducing BP in a controlled manner without reducing uteroplacental perfusion, which causes fetal heart rate decelerations. The goal is not to make the patient normotensive but rather to reduce the patient's systolic BP to 140 to 155 mm Hg and the diastolic BP to 90 to 105 mm Hg. If unable to achieve the systolic range, more importance is placed on bringing down the diastolic value