Medical ComplicationIn'PregnancyDiabetes
Medical Complication In Pregnancy Diabetes
Atthe beginning of the 20thcentury , diabetic women sufferedfrom infetility, and the rare womenachieving pregnancy faceda poorprognosis.Maternal death was areal threat,and perinatal survival amore4opercent
At the beginning of the 20th century , diabetic women suffered from infetility, and the rare women achieving pregnancy faced a poor prognosis. Maternal death was a real threat,and perinatal survival a more 40 percent
Theavailability of insulinsince 1922restored fertility and virtuallyabolished maternal mortality.At/the sametime,perinatalsurvivaldid not change appreciatably.Since1949WhiteClassificationwasdeveloped, permitted individualizedtiming and mode of delivery, thenperinatal mortality was reduced(nearly equivalent to that observedin normalpregnancies.)
The availability of insulin since 1922, restored fertility and virtually abolished maternal mortality. At the same time, perinatal survival did not change appreciatably. Since 1949 White Classification was developed, permitted individualized timing and mode of delivery, then perinatal mortality was reduced (nearly equivalent to that observed in normal pregnancies.)
I.classificationTypeIDiabetesMellitus.---insulin-dependent.---immune-mediatedanddevelopedin geneticallysusceptiblepersons.---concordanceratefordiabetesinmonozygoustwinsislessthan50%
I. Classification Type I Diabetes Mellitus -insulin-dependent -immune-mediated and developed in genetically susceptible persons -concordance rate for diabetes in monozygous twins is less than 50%
TypeIl diabetes-noninsulin-dependent---no HLAassociation---familialoccurrence---concordanceratefor diabetesinmonozygoustwinsis100%
Type II diabetes -noninsulin-dependent -no HLA association -familial occurrence -concordance rate for diabetes in monozygous twins is 100%