IF: Granular pattern in capillary walls
IF: Granular pattern in capillary walls
EM: Electron dense deposites in the capillary wall
EM: Electron dense deposites in the capillary wall
Immune complex nephritis in situ mainly caused by endogenous tissue antigen or cationic proteins 1. Anti-gbm disease Goodpasture syndrome antigen: a3 NCI of type IV collagen self-ab bind to gbm or LBm
• Immune complex nephritis in situ mainly caused by endogenous tissue antigen or cationic proteins 1. Anti- GBM disease Goodpasture syndrome --- antigen: α3 NCI of type IV collagen self-Ab bind to GBM or LBM
Basement membrane Anti-GBM GBM antigen Glomerulonephritis Fc rece complement PMN Epithelial Anti-GBM antibody processes ● granule protein c Endothelial cel
IF linear pattern EM: No electron dense deposit
IF: linear pattern EM: No electron dense deposit