Factors that affect the concentration and dilution of the urine 1)Damage of renal medulla Resulting in an impairment of the concentrating abili 2) Loop diuretics such as frusemide, inhibiting the Na/K/2Cl co transport system in the thick ascending limb
Factors that affect the concentration and dilution of the urine 1) Damage of renal medulla Resulting in an impairment of the concentrating ability 2) Loop diuretics such as frusemide, inhibiting the Na+ / K+ / 2Cl- cotransport system in the thick ascending limb
Factors that affect the concentration and dilution of the urine 3)Lack of urea in the body such as maLnutrition, reducing the osmotic gradient established in the renal medulla 4)Increased velocity of blood flow in the vasa recta carrying away amount of naci -> reducing the osmotic gradient in the medulla
Factors that affect the concentration and dilution of the urine 3) Lack of urea in the body such as malnutrition, reducing the osmotic gradient established in the renal medulla 4) Increased velocity of blood flow in the vasa recta carrying away amount of NaCl → reducing the osmotic gradient in the medulla