上游充通大￥ SHANGHAI JIAO TONG UNIVERSITY 生物力学的发展前景 梁夫友 船舶海洋与建筑工程学院 上海交通大学
生物力学的发展前景 船舶海洋与建筑工程学院 上海交通大学 梁夫友
个性化医疗(Personalized Medicine) 上游充通大粤 SHANGHAI JIAO TONG UNIVERSITY Personalized medicine is a medical model that proposes the customization of healthcare,with decisions and practices being tailored to the individual patient by use of genetic or other information ICited from Wikipadial 758万条 2012年到月 .w ftni之d四a回 牌平料 2730万条 22-2 2013年1月 enay2222 g4-444n年中件华m G下Gos0 单arsonlged medicins 多和提理 细面时学种即家 有2,700,00，位是第1页 3270万条 2015年2月 一年内
Personalized medicine is a medical model that proposes the customization of healthcare, with decisions and practices being tailored to the individual patient by use of genetic or other information [Cited from Wikipadia] 2012年9月 2013年11月 2015年2月 758万条 2730万条 3270万条 个性化医疗（Personalized Medicine）
为什么需要个性化医疗？ 上游充通大学 SHANGHAI JIAO TONG UNIVERSITY General medicine Population- Contradictory Individual based trends treatment plans variability Personalized medicine Population- Individual Well-suited based trends variability treatment plans [Kilner et al,Nature,2000; Gebker et al.J.Cardiovasc.Magn.Reson.2007; Ecabert and Smith.Newsroom,SPIE,2010]
为什么需要个性化医疗? [Kilner et al, Nature, 2000; Gebker et al. J. Cardiovasc. Magn. Reson. 2007; Ecabert and Smith. Newsroom, SPIE, 2010] Contradictory treatment plans Populationbased trends Individual variability General medicine Populationbased trends Individual variability Personalized medicine + Well-suited treatment plans
瓶颈问题 上游充通大￥ SHANGHAI JIAO TONG UNIVERSITY ·信息不足（临床检测手段有限） ·不可预知性（手术前后血流变化无法准确预测）
瓶颈问题 ▪信息不足（临床检测手段有限） ▪不可预知性（手术前后血流变化无法准确预测）
解决方案 上游充通大粤 SHANGHAI JIAO TONG UNIVERSITY Cardiovascular pathophysiology Experimental methods Computational methods (In vivo vascular imaging,hemodynamic measurements) (Hemodynamic computations&physiological simulations) Higher precision Easier operation Higher fidelity Flexible simulation Personalized and predicative medicine
Higher precision & Easier operation Computational methods (Hemodynamic computations& physiological simulations) Experimental methods (In vivo vascular imaging, hemodynamic measurements) Higher fidelity & Flexible simulation Cardiovascular pathophysiology Personalized and predicative medicine 解决方案