Section I Central immune organs
Section I Central immune organs
I Bone marrow 1. The bone marrow is the site of generation of all circulating blood cells in the adult, including immature lymphocytes
I. Bone marrow 1. The bone marrow is the site of generation of all circulating blood cells in the adult, including immature lymphocytes
Self-renewing enter progenitor Pluripotent stem cell Thymus Natural killer (NK)cell B lym T lymphocytes 。 Erythroid CFU Megakaryocyte Basophil CFU Eosinophil CFU Granulocyte-monocyte CFU Erythrocytes Platelets Basophils Eosinophils Neutrophils Monocytes Figure 2-7 Hematopoiesis. The development of the different lineages of blood cells is depicted in this "hematopoietic tree. The regulation of hematopoiesis by cytokines is illustrated in Chapter 11, Figure 11-18, CFU, colony-forming unit
Self-renewing stem cells Pluripotent stem cells( CD34+ Stem cell antigen-1) Myeloid progenitor and lymphoid progenitor Thymus B cells t cells and nk cells Erythroid, magkaryocyte, Basophil, Eosinophil ganulocyte-monocyte lineage erythrocyte platelets basophils eosiniphils neutrophils, monocytes
Stem cell Pro-B Pre-B Immature B Mature B 2. The bone marrow is the site of b cell maturation
2. The bone marrow is the site of B cell maturation