Chapter III General introduction of immune system
Chapter III General introduction of immune system
Immune system Immune organs or tissues bone marrow thymus spleen lymph nodes Immune cells lymphocytes: T cells, b cells and nK cells phagocytes: Dendritic cells macrophage PMN immune molecules antibod complement(补体) cytOKines adhesive molecules
Immune system immune organs or tissues bone marrow thymus spleen lymph nodes Immune cells : lymphocytes : T cells , B cells and NK cells phagocytes: Dendritic cells ,macrophage ,PMN immune molecules : antibody complement (补体） cytokines adhesive molecules
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Immune organs a Central immune organs or primary lymphoid organs The site that lymphocytes generate and mature into functional cells Bone marrow and thymus Peripheral immune organs or secondary lymphoid organs and tissues The sites that t and b lymphocytes reside in and respond to antigens spleen, lymph nodes, mucosal or cutaneous lymphoid tissues
Immune organs ◼ Central immune organs or primary lymphoid organs The site that lymphocytes generate and mature into functional cells Bone marrow and Thymus ◼ Peripheral immune organs or secondary lymphoid organs and tissues The sites that T and B lymphocytes reside in and respond to antigens spleen , lymph nodes , mucosal or cutaneous lymphoid tissues
Central lymphoid organs Peripheral lymphoid organs Recirculation B lymphocytes Bone marrow stem cell B lymphocyte Bursa of Fabricius(birds) Blood Lymph nodes lineage Bone marrow(mammals) Spleen Mucosal and T lymphocyte Thymus Blood cutaneous neage lymph lymphoid tissues T lymphocytes Recirculation Figure 2-2 Maturation of lymphocytes Development of mature lymphocytes before antigen exposure occurs in the generative lymphoid organs, and immune responses to foraign antigens occur in the peripheral lymphoid tissues