(5)Pathologicalchanges1 Gross: Enlarged and pale kidneyLM:Early stageGlomeruliiappearnormalLater国Uniform, diffuse thickening ofglomerular capillary wall
(5) Pathological changes ① Gross: Enlarged and pale kidney ② LM: Early stage Glomeruli appear normal Later Uniform, diffuse thickening of glomerular capillary wall
MembranousGN(PAS stain)中
Membranous GN( PAS stain )
swelling of podocyte③EM3 - loss of foot processes- dense deposits in thesubepithelial cells
③EM ▪ swelling of podocyte ▪ loss of foot processes ▪ dense deposits in the subepithelial cells
EpitheliumwitheffacedfootprocessesThickenedbasementmembraneSubepithelialdepositsD
GNMembranous
Membranous GN