革山院 Definition Chronic kidney disease( CKD) Chronic renal failure (CrF) End stage renal diseases (ESrD) Uremia
Definition • Chronic kidney disease (CKD) • Chronic renal failure (CRF) • End stage renal diseases (ESRD) • Uremia
革山院 Definition Chronic kidney disease(CKd) A spectrum of different pathophysiologic processes associated with abnormal kidney function and a progressive decline in GFR A spectrum of clinical problems beginning with abnormalities detectable only by laboratory testing to a late stage, labeled uremia
Definition • Chronic kidney disease (CKD) – A spectrum of different pathophysiologic processes associated with abnormal kidney function and a progressive decline in GFR – A spectrum of clinical problems beginning with abnormalities detectable only by laboratory testing to a late stage, labeled uremia
革山院 Definition Chronic renal failure(Crf) a pathophysiologic process with multiple causes that lasts >3 months and results in progressive, irreversible attrition of the number and function of nephrons Typically corresponds to CKd stages 3-5 Frequently leads to end-stage renal disease (ESrD)
Definition • Chronic renal failure (CRF) – A pathophysiologic process with multiple causes that lasts > 3 months and results in progressive, irreversible attrition of the number and function of nephrons – Typically corresponds to CKD stages 3–5 – Frequently leads to end-stage renal disease (ESRD)
革山院 Definition End stage renal diseases ( esrd) Clinical state in which irreversible loss of endogenous renal function has occurred Patients are permanently dependent on renal replacement therapy to avoid life-threatening uremia CKD Stage 5 Uremia a clinical syndrome reflecting dysfunction of all organ systems due to untreated or undertreated acute or chronic renal failure
Definition • End stage renal diseases (ESRD) – Clinical state in which irreversible loss of endogenous renal function has occurred – Patients are permanently dependent on renal replacement therapy to avoid life-threatening uremia. – CKD Stage 5 • Uremia – A clinical syndrome reflecting dysfunction of all organ systems due to untreated or undertreated acute or chronic renal failure
Stage and prevalence of cKd GFR Prevalence Stage Description (m/min/1.73 N m (1000s) Kidney Damage 1 with normal or个 ≥90 5,9003.3 GFR Kidney damage 60-89 5,30030 234 with mild↓GFR Moderate√GFR 30-59 7.6004.3 Severe」GFR 15-29 4000.2 Kidney Failure <15 or Dialysis 3000.1
Stage and Prevalence of CKD Stage Description GFR (ml/min/1.73 m2 ) Prevalence N (1000s) % 1 Kidney Damage with Normal or GFR 90 5,900 3.3 2 Kidney Damage with Mild GFR 60-89 5,300 3.0 3 Moderate GFR 30-59 7,600 4.3 4 Severe GFR 15-29 400 0.2 5 Kidney Failure < 15 or Dialysis 300 0.1